The Effectiveness of Chitosan as an Antimicrobial on Bacterial Cellulose-based Scaffold Skin Tissue Engineering

Khatarina Meldawati Pasaribu, Saharman Gea, Tamrin, Safruddin Ilyas

2019

Abstract

Bacterial cellulose (BC) is known to be used as a scaffold for tissue engineering. However, pristine BC is not ideal enough to be applied as a scaffold because bacterial cellulose does not have antimicrobial activity. The aim of this study was to evaluate the antmicrobial activity of bacterial cellulose and their composites. BC gel, produced by Acetobacter xylinum with HS medium as a carbohydrate resources, was immersed into chitosan (Ch) and collagen (Co) by ex-situ approach to produce BC/Ch/Col. The same procedures were repeated for BC/Ch, BC/Col, and BC/Col/Ch. The effectiveness of antimicrobial activity was carried out using disk paper to inhibit the growth of pathogen bacteria such as Escherichia coli and Staphylococcus aureus. The results showed that BC/Ch has the highest antimicrobial activity against E. coli and S. aureus with the inhibition zone of 10.15 mm and 7.9 mm, respectively.

Paper Citation

in Harvard Style

Pasaribu K., Gea S., Ilyas S. and Tamrin. (2019). The Effectiveness of Chitosan as an Antimicrobial on Bacterial Cellulose-based Scaffold Skin Tissue Engineering.In Proceedings of the 1st International Conference on Chemical Science and Technology Innovation - Volume 1: ICOCSTI, ISBN 978-989-758-415-2, pages 178-181. DOI: 10.5220/0008864701780181

in Bibtex Style

@conference{icocsti19,
author={Khatarina Meldawati Pasaribu and Saharman Gea and Safruddin Ilyas and Tamrin},
title={The Effectiveness of Chitosan as an Antimicrobial on Bacterial Cellulose-based Scaffold Skin Tissue Engineering},
booktitle={Proceedings of the 1st International Conference on Chemical Science and Technology Innovation - Volume 1: ICOCSTI,},
year={2019},
pages={178-181},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008864701780181},
isbn={978-989-758-415-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Chemical Science and Technology Innovation - Volume 1: ICOCSTI,
TI - The Effectiveness of Chitosan as an Antimicrobial on Bacterial Cellulose-based Scaffold Skin Tissue Engineering
SN - 978-989-758-415-2
AU - Pasaribu K.
AU - Gea S.
AU - Ilyas S.
AU - Tamrin.
PY - 2019
SP - 178
EP - 181
DO - 10.5220/0008864701780181