Improvement of Renal Proximal Tubules after Black Cumin (Nigella Sativa) Extract Administration in Rat with CCl4-induced Chronic Renal Damage

Fathiyah Safithri, Desy Andari, Fifa Yuniarmi

2019

Abstract

Chronic renal disease is a chronic pathological process in renal that accompanied by a progressive decline in renal function and generally ends up as renal failure. Chronic inflammation and oxidative stress are key factors in progression. Black cumin extract has antioxidant and anti-inflammatory effects that is thought to repair renal tubular and inhibit progression of the damage. Objectives: to evaluate the improvement of renal proximal tubules in rat with CCl4-induced chronic renal damage after black cumin extract administration. Results: The result showed that the amount of hyaline cast in the proximal tubule significantly decreased after black cumin extract adminstration. Conclusion: Black cumin extract decreases the amount of hyaline cast in the proximal tubule. The antioxidant and anti-inflammatory effects of Black cumin extract may modulate the improvement renal tubular.

Paper Citation

in Harvard Style

Safithri F., Andari D. and Yuniarmi F. (2019). Improvement of Renal Proximal Tubules after Black Cumin (Nigella Sativa) Extract Administration in Rat with CCl4-induced Chronic Renal Damage.In Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC, ISBN 978-989-758-462-6, pages 21-26. DOI: 10.5220/0009120000210026

in Bibtex Style

@conference{hsic19,
author={Fathiyah Safithri and Desy Andari and Fifa Yuniarmi},
title={Improvement of Renal Proximal Tubules after Black Cumin (Nigella Sativa) Extract Administration in Rat with CCl4-induced Chronic Renal Damage},
booktitle={Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC,},
year={2019},
pages={21-26},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009120000210026},
isbn={978-989-758-462-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC,
TI - Improvement of Renal Proximal Tubules after Black Cumin (Nigella Sativa) Extract Administration in Rat with CCl4-induced Chronic Renal Damage
SN - 978-989-758-462-6
AU - Safithri F.
AU - Andari D.
AU - Yuniarmi F.
PY - 2019
SP - 21
EP - 26
DO - 10.5220/0009120000210026