Characterization and Antibacterial Activity of Dayak Onion (Eleutherine palmifolia) Hydrogel in Vitro

Uswatun Chasanah, A. B. Apriliyanto, D. Anggara, Ayu Kusumawardani, Dian Ermawati

2019

Abstract

Traditionally, the crushed bulbs of Dayak onion (Eleutherine palmifolia) used for wound healing due to naphthoquinone compounds found in the bulbs of Dayak onion can inhibit the growth of Staphylococcus aureus, Staphylococcus epidermis, and Pseudomonas aeruginosa that cause skin infection. To improve the ease of using the bulbs of Dayak onion as drugs for the treatment of wounds that need to be made in the appropriate dosage form is a topical hydrogel, hydrogels contained Dayak onion extract at a level of 2%, 4.5%, and 6.0% were made then determined its characterization which included organoleptic, pH, viscosity, and spreadability, determined of antibacterial activity by a well-diffusion method. The higher levels Dayak onion extract resulted in hydrogels which homogenous, sharp color intensity, more aromatic, decreased viscosity, and increased spreadability while for pH was not different, while the highest antibacterial activity achieved by Dayak onion hydrogels 6.0% which had antibacterial effectiveness to the Staphylococcus aureus, Staphylococcus epidermis, and Pseudomonas aeruginosa were 59.2%, 49.5%, and 63.1%, respectively, and as control was tetracycline HCL 1.0%. Thus, the Dayak onion hydrogels 6.0% is the best.

Paper Citation

in Harvard Style

Chasanah U., Apriliyanto A., Anggara D., Kusumawardani A. and Ermawati D. (2019). Characterization and Antibacterial Activity of Dayak Onion (Eleutherine palmifolia) Hydrogel in Vitro.In Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC, ISBN 978-989-758-462-6, pages 164-170. DOI: 10.5220/0009126201640170

in Bibtex Style

@conference{hsic19,
author={Uswatun Chasanah and A. B. Apriliyanto and D. Anggara and Ayu Kusumawardani and Dian Ermawati},
title={Characterization and Antibacterial Activity of Dayak Onion (Eleutherine palmifolia) Hydrogel in Vitro},
booktitle={Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC,},
year={2019},
pages={164-170},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009126201640170},
isbn={978-989-758-462-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC,
TI - Characterization and Antibacterial Activity of Dayak Onion (Eleutherine palmifolia) Hydrogel in Vitro
SN - 978-989-758-462-6
AU - Chasanah U.
AU - Apriliyanto A.
AU - Anggara D.
AU - Kusumawardani A.
AU - Ermawati D.
PY - 2019
SP - 164
EP - 170
DO - 10.5220/0009126201640170