Antibacterial and Characterization of Secondary Metabolite Compound from Ethyl Acetate and Ethanol Fraction of Leaves Moringa oliefera L

Siti Rofida

2019

Abstract

The microorganisms that cause infections can mutate due to excessive antibiotic exposure. One of the new drug search strategies is through the exploration of active ingredients derived from plants that have been used empirically by the community. Moringa oleifera L leaf is a plant that has been used and has been shown to have antibacterial, antifungal, analgesic, and antihypertensive activities. Moringa oleifera L leaves contain secondary metabolites such as alkaloids, tannins, saponins, flavonoids, and phenols. The purpose of this study was to obtain active ingredients from the leaves of Moringa oleifera L which will be used as a Standardized Herbal Medicine product in the treatment of infectious cases. In order to get the active ingredient as an antibacterial, multilevel extraction is carried out using different polarity solvents, so that a fraction containing nonpolar, semipolar and polar compounds will be obtained. Antimicrobial potential will be tested on each fraction using the disk diffusion method. The results of identification of the compounds in the ethyl acetate fraction show the class of compounds Flavonoids, Terpenoids, Polyphenols and Anthraquinone while in the ethanol fraction Moringa oleifera L. leaves show the compounds of the compounds Alkaloids, Flavonoids, Terpenoids, Polyphenols, and Saponin. Antimicrobial activity is shown in the ethyl acetate and ethanol fraction in both Staphylococcus aureus and Escherichia coli.

Paper Citation

in Harvard Style

Rofida S. (2019). Antibacterial and Characterization of Secondary Metabolite Compound from Ethyl Acetate and Ethanol Fraction of Leaves Moringa oliefera L.In Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC, ISBN 978-989-758-462-6, pages 233-239. DOI: 10.5220/0009141002330239

in Bibtex Style

@conference{hsic19,
author={Siti Rofida},
title={Antibacterial and Characterization of Secondary Metabolite Compound from Ethyl Acetate and Ethanol Fraction of Leaves Moringa oliefera L},
booktitle={Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC,},
year={2019},
pages={233-239},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009141002330239},
isbn={978-989-758-462-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Health Science International Conference - Volume 1: HSIC,
TI - Antibacterial and Characterization of Secondary Metabolite Compound from Ethyl Acetate and Ethanol Fraction of Leaves Moringa oliefera L
SN - 978-989-758-462-6
AU - Rofida S.
PY - 2019
SP - 233
EP - 239
DO - 10.5220/0009141002330239