An Experiment for Soy Peptide Investigation Effect on Brain Wave

Activity with EEG Signals

Arjon Turnip

1,2

, Dwi Esti Kusumandari

, Dessy Novita

, and Narendra Duhita

Technical Implementation Unit for Instrumentation Development, Indonesian Institute of Sciences, Indonesia

Department of Electrical Engineering, Universitas Padjadjaran, Indonesia

R & D Department, PT. Amerta Indah Otsuka, Indonesia

Keywords: EEG, Brain Wave, Methadone, Stimuli.

Abstract: Peptide is a protein component consist of amino acids. Brain function is influenced by protein intake, the

nutrients that are also composed of various types of amino acids. Protein is needed in the formation of brain

cells in certain parts, including the hippocampus and brainstem or brain stem. Therefore, foods made from

soy can be a good intake to improve brain performance. In this study, an experiment using an EEG system

with 19 channels electrodes was carried out. In the experiment 17 people of subjects with age around 22

were chosen. Each subject were fasted at least 8 hours before recording data. In a relaxed state while closing

eyes, data were recorded just before and 1 hour after consuming soy peptides, respectively. From the results

of data processing, it was found that brain wave activity tends to increase due to consuming foods made

from soybeans. An average increase in brain wave amplitude of about 5% was found.

1 INTRODUCTION

The benefits of soybeans to educate the brain has

long been known by most people, even soybeans

themselves are made into lecithin for the basic

ingredients of herbal medicine for brain intelligence.

Besides being able to educate the brain, soy is also

very good for providing adequate nutrition to the

body, because soy itself is a very high source of

protein. Soybean which is a material for making tofu

and tempeh, it turns out in countries like China and

Japan are often used as food that is often consumed,

and the results you can see, the country has a very

high level of health. Soybeans are not a luxury item

in Indonesia, in fact there are many soy farmers and

how to grow soybeans is very easy, but

unfortunately most people are not aware of the

benefits of soybeans.

In soybeans, there are some nutritional content

that is very good for health (Chatterjee, Gleddie, and

Xiao, 2018; Valliyodan et al. 2016; Huang,

Krishnan, Pham, Yu Wang, 2016; Singh, Vij, Hati,

2014; Zaheer, Humayoun, 2017; Lule, et al. 2015).

In addition, soybeans can make the body become

powerful. In addition to protein, soybeans also

contain fat in them, so it's only natural that weight

will increase when eating too much soybeans (De

Angelis, Pilolli, Bavaro, Monaci, 2017; Lammi C.,

Zanoni C., Arnoldi, 2015; Yoshikawa, 2015; Lammi

et al, 2015; Jamilian, Asemi, 2015; Oliva, Chicco,

Lombardo, 2015; Cruz-Huerta et al, 2015). Although

soybeans contain fat, but the fat produced by

soybeans is good fats such as omega 3 fatty acids.

The omega 3 fat content in soybeans is what makes

the benefits of soybeans to educate your brain,

because omega 3 is very good for brain tissue.

Omega 3 is usually found in sea fish, but the price of

sea fish that contains omega 3 is very expensive, so

you can make soybeans as an alternative to sea fish

as a source of omega 3. For those of you who are

still school students, you should be diligent in

consuming soybeans so that the brain becomes

smart. You can also consume tofu and tempeh every

day, because tofu and tempeh come from soybeans

which are very good for brain intelligence. Working

throughout the day is very draining, both physically

and mentally. The fatigue caused by it can make

concentration decrease, so productivity decreases. In

conditions like this, the brain needs peptides. Peptide

is a protein component consisting of 3-20 amino

acids. Almost the same as protein, it's just the

Turnip, A., Kusumandari, D., Novita, D. and Duhita, N.

An Experiment for Soy Peptide Investigation Effect on Brain Wave Activity with EEG Signals.

DOI: 10.5220/0009448700050012

In Proceedings of the International Conference on Health Informatics and Medical Application Technology (ICHIMAT 2019), pages 5-12

ISBN: 978-989-758-460-2

amount of amino acids that make it up less. A study

conducted by a team of researchers from Japan and

Indonesia in 1996 also revealed that peptides can

increase concentration.

The Food and Drug Administration (FDA) has

approved claims of the results of research conducted

by (Huang et, al, 2016; Velasquez & Bhathena,

2007; Xiao, 2008; Young, 1991) which is the health

of foods that link soy protein with a reduced risk of

coronary heart disease. Soy is a source of high

quality protein that contains all the essential amino

acids found in animal protein without cholesterol

and with a little saturated fat. Other studies have also

proven the potential benefits of soy in reducing the

risk of chronic diseases such as obesity,

cardiovascular disease, insulin-resistant diabetes,

and certain types of cancer (Huang et, al, 2016;

Xiao, 2008; Young, 1991; Erdmann, et al, 2008;

Kwon et al, 2010). Soy protein and phytochemicals,

especially isoflavones, are believed to be responsible

for these benefits. A total of 2 to 20 amino acid

lengths are absorbed by the intestine into the blood

circulation to exert a systemic orlokal physiological

effect in the target tissue (Erdmann, et al, 2008;

Kwon et al, 2010). Maebuchi et al. has proven that

intestinal absorption of 11S peptides in humans

results in a significant increase in the concentration

of amino acids in venous blood globulin11S

(Maebuchi, 2007). These differences (important for

aromatic and branched amino acid chains) also

indicate that hydrolyzed soy protein is faster and

more efficiently absorbed in humans (Maebuchi,

2007).

Bansal and Parle, 2010 shows that consumption

of foods made from soybeans not only improves

memory but also can reverse memory deficits with

its diverse activities. This nutritional potential is also

thought to be beneficial to explore in the

management of Alzheimer's disease. Dementia

usually occurs due to Alzheimer's disease in the

form of progressive neurodegenerative disorders.

The process of dementia starts from the loss of

neurons in different parts of the brain (Shineman &

Fillit, 2009). In addition to drugs, dementia can also

be minimized with food supplements with nutrition

and soy can be one type of nutrition. (Kreijkamp-

Kaspers et al, 2004; Lee & Sohn, 2005; McEwen,

2001) Shows the Effect of the soy protein of the

human brain especially in the cognitive function).

Soy isoflavones have an estrogenic effect, and it has

been reported that soy isoflavones may improve

cognitive functions by mimicking the effects of

estrogen (especially through estrogen receptor β) in

the brain (McEwen, 2001). Various studies have

shown that estrogen can significantly enhance the

basal forebrain cholinergic function by increasing

the uptake of choline, and stimulating acetylcholine

release (Thakur & Sharma, 2006). Acetylcholine is

considered as the most important neurotransmitter

involved in the regulation of cognitive functions.

There is extensive evidence linking the central

cholinergic system to the memory. Cognitive

dysfunction has been shown to be associated with

impaired cholinergic function and the facilitation of

central cholinergic activity, with improved memory.

Soy isoflavones are reported to increase cholinergic

transmission due to indirect facilitation of

acetylcholine in the brain (Sharma, 1997; Parle,

2004). An excellent source of dietary peptides, have

beneficial effects on health. We investigated the

effect of the soybean peptide on immune function,

brain function, and neurochemistry in healthy

volunteers. Near-infrared spectroscopy (NIRS) was

used to analyze brain cerebral blood flow (Yimit et

al, 2012). From some sources believe and some have

proven that soypeptide is able to affect the

functional brain in several categories. In this paper,

the effect before and after consuming soypeptide on

brain function activity was tested in an experiment

using EEG signals. We have done a lot of research

on brain activity using EEG signals (Iskandar, et al,

2019, Turnip at al, 2018, Turnip, Kusumandari,

Hidayat, Hidayat, 2018, Turnip, Kusumandari, and

Pamungkas, 2019). Subjects: 17 voluntary subject

brain activity was measured. The findings show that

an increase in brain activity after one hour

consuming soy peptide was found. Figure 1 shows

the original form of soybean as a basic ingredient of

soy peptide and has been shown to be able to

increase brain signal activity.

Figure 1: Soybean as a basic ingredient of soy

peptide and its effect on brain activity.

ICHIMAT 2019 - International Conference on Health Informatics and Medical Application Technology

2 METHODS

Based on previous research, that the protein

content especially obtained from soybeans is closely

related to body health, one of which is the human

brain. PT Amerta Indah Otsuka is developing a food

product made from soy ingredients known as soy

peptides and it is thought that these products have a

role in increasing blood flow to the brain. For

testing, an experiment using 17 narcotics was

designed. Subjects involved in the experiment were

students with age around 20 ± 3 years and all were

male. The experiment was carried out for 3

consecutive days. Each subject was asked to fast at

least 8 hours before data recording was performed.

Data recording was performed three times for each

subject that is before, 5 after, and 1 hour after

consuming soy peptides. Before recording, each

subject described an experimental scenario but not

for the purpose of the experiment. The reason the

purpose of the experiment was not explained is to

minimize the possibility of the subject becoming less

concentrated in following the instructions.

Recording before consuming soy peptide is to see

brain activity in the initial conditions and recording

after one hour aims to see changes in the amplitude

of brain wave activity after food reaches the brain

through the bloodstream.

An EEG system with 19 electrode channels is

mounted on the head of each subject. To increase the

conductivity of the electrodes with brain signals, an

introductory gel is placed between the scalp and

each electrode. During the experiment each subject

was asked to relax while closing his eyes. Data

recorded each for 5 minutes for each session. After

completing the recording process, each subject was

asked to fill in informed consent and was given a

transport fee of Rp 100,000. The process of

recording EEG data during an experiment can be

seen as in Figure 2.

Every electrode used must be connected to the

WinEEG software. So that the calibration of each

electrode that has been given an electrode gel can be

seen in the WinEEG software. The calibration of

each electrode that has been given an electrode gel

will look slightly colored, if the yellow color is very

good, if the red color is pretty good, and if the black

color indicates the electrodes do not work. In the

picture below is the impedance of each electrode

point after being given an Electro-Gel at each

channel point used. The tools used in the experiment

is shown in Figure 3. Actually the EEG tool used has

more channel capacity than used. But we only need

19 channels. If there are too many channels, the

signal processing time will be longer and more

difficult. (Figure 3 a). Electro-cup size to the size of

the head of each subject affects the quality of the

measurement. This quality can usually be observed

in the form of noise contamination in data records. If

the head size is smaller or we are smaller than the

size of the electro-cup, then the sensor contact with

the head will be smaller. This condition causes the

signal conductivity to decrease (Figure 3b). A

decrease in the conductivity level will be seen in

FIgure 3c where the color tends to yellow to red. If

the subject's head size is smaller than the electro-cup

size, the installation process tends to be more

difficult and sensitive to subject movement.

Figure 2: Experimen setup of soy peptida effect on

brain wave activity.

Figure 3: Experiment Tools: (a) EEG Mitsar 202 (31

Channels), (b) Electro-cup, (c) Electro-conductivity.

An Experiment for Soy Peptide Investigation Effect on Brain Wave Activity with EEG Signals

Overall this research method can be represented by a

scheme as in Figure 4. With an experimental

designed scheme, this research is expected to

produce changes in brain signal activity after

consuming soy peptide through an increase in

amplitude and can be represented in the form of 2D

brain mapping.

Figure 4: Experiment and Signal Processing

Scheme.

3 RESULTS AND DISCUSSIONS

After processing the raw data and filtering the signal

(0.5-70 Hz Cut off frequency), feature extraction is

obtained where the feature is obtained from

manually cutting data in accordance with the amount

of data we have and the desired information. The

amplitude of the results of truncation of EEG signal

data can be seen as in Tables 1-4. Tables 1-3 from

subject 14 show the amplitude of brain waves for

each channel that is before, after 5 minutes, and after

1 hour consuming soy peptides, respectively. For all

tables it is obtained that all maximum amplitudes

occur in the desired frequency range except Alpha

waves on the channels associated with the FP1

channel in Table 1; FP1 and FP2 on Tables 2 and 3.

It is suspected that these two channels experienced

interference at the time of recording. Because the

recording is done on the condition of the subject

relaxed and closed eyes, the results found also match

where the highest amplitude is what the low

frequency range is alpha waves. The high amplitude

of delta waves is more likely to be thought to be due

to disturbance such as based lines, eyeball

movements, and body movements in the frequency

range of 0 -4 Hz. Figure 5 indicates the Comparison

of the brain wave amplitude: Closed & Open Eyes

and Pre, Pra, & After 1 Hours. Grafik tersebut

menunjukkan bahwa amplitudo pada saat closed

eyes cenderung lebih tinggi terhadap closed eyes

artinya subjek lebih konsentrasi pada saat closed

eyes. Significant differences occur only in alpha

waves when compared with other brain waves at

different frequency ranges. It can be concluded that

only in alpha waves occurs the most dominant brain

activity. If you pay further attention to the increase

in the amplitude of alpha waves before, 5 minutes

after and 1 hour after consuming soy peptides,

respectively, a significant increase in amplitude was

found at around 40%. This increase indicates a

significant effect due to consuming soy peptides on

brain activity. Table 4 indicates the comparison of

the brain wave amplitude for all subjects.

Table 1: Pre: Amplitude of each channels of each

brain wave.

Table 2: Pra: Amplitude of each channels of each

brain wave.

The same thing is also seen in Table 4 where

the highest amlitude is found in alpha waves for all

subjects. Strangeness is found in subjects 5, 14, and

16 where the average amplitude is very low

compared to other subjects, namely in experiments

before and 5 minutes after consuming soy peptides.

This difference is thought to be temporary due to

errors in processing data. The strangeness of this

data will be a special study in the following

% Hz % Hz % Hz % Hz % Hz % Hz

Fp2‐F8 36,54 1,46 10,12 4,15 8,77 7,57 2,43 16,36 3,77 24,17 2,93 30,27

F8‐T4 24,46 1, 46 8,36 3,91 17,02 10,99 4,6 17,82 7, 79 22,95 6,49 30,52

T4‐T6 16,12 1,71 6,25 4,39 40,84 10,99 4,15 17,58 6,32 22,95 3,81 32,23

T6‐O2 15,83 1,46 9,5 4,15 47,2 10,99 3,57 13,92 4,78 21,73 2,23 30,76

Fp1‐F7 30 1,46 9, 64 4,15 10,13 7,32 2, 66 14, 16 3,19 20,02 2,09 30,03

F7‐T3 22,32 1,46 7,4 4,15 17,86 10,99 3,66 19,29 5,94 23,68 4,48 29,79

T3‐T5 10,39 1,46 4,71 4,15 44,21 10,99 4,66 19,78 9,63 22,46 6,95 38,09

T5‐O1 13,41 1,71 7, 89 4,15 54,39 10,99 3,61 13,92 5,74 29,79 2,86 29,79

Fp2‐F4 42,27 1,46 9,5 4,15 7,59 7,57 2,19 17,58 2,72 20,02 1,6 30,03

F4‐C4 28,07 1,46 12,78 3,91 22,26 10,99 3,72 13,92 4,29 21,73 1,98 30,27

C4‐P4 19,16 1,46 7, 69 3,91 43,78 10,99 3,31 13,92 3,89 22,22 1,34 30,03

P4‐O2 21,02 1,46 9,27 4,15 38,79 10,99 3,54 14,4 5,43 21,73 1,77 30,76

Fp1‐F3 36,22 2,2 10,51 3,91 9,32 12,45 2,67 14,16 3,24 20,02 1,83 29,79

F3‐C3 26,17 1,46 11,09 3,91 29,29 12,45 3,45 13,92 4,51 21,24 1,62 30,03

C3‐P3 15,47 1,46 6, 98 3,91 53,94 10,99 3,13 13,92 5,01 21,73 1,4 29,79

P3‐O1 14,06 1,46 7,83 5,13 54,51 10,99 3,77 13,92 6,1 21,73 1,77 29,79

Fz‐Cz 24,71 1,46 12,42 5,62 28,5 12,45 3,81 13,92 4,41 23,44 1,9 30,27

Cz‐Pz 2 4,61 1,46 9,5 3,91 31,75 10,99 3,19 13,92 3,41 21,24 1,32 31,01

Average 23,38 1,53 8,97 4,21 31,12 10,65 3,45 15,36 5,01 22,38 2,69 30,74

Beta2 Gamma

Channels

Delta Theta Alpha Beta1

% Hz % Hz % Hz % Hz % Hz % Hz

Fp2‐F8 34,01 1,46 7,19 4,39 6,05 8,79 2,32 18,07 3,86 21 4 33,2

F8‐T4 19,39 1,46 6,03 3,91 9,21 10,99 3,81 18,07 9,38 22,46 12,05 31,25

T4‐T6 22,11 1,46 4,45 3,91 16,85 10,99 2,24 13,92 5,56 27,59 6,89 31,25

T6‐O2 23,27 1,46 9,08 3,91 32,37 10,99 3,75 14,16 4,64 21,48 2,81 31,25

Fp1‐F7 34,11 1,46 6,64 3,91 5,94 10,99 2,14 13,92 3,46 23,44 3,76 37,35

F7‐T3 22,3 1,46 4,53 3,91 8,2 10,99 3,36 19,29 9,07 24,41 7,55 29,79

T3‐T5 19,42 1,46 3,73 3,91 15,43 10,99 4,09 19,04 8,32 24,41 9,3 31, 98

T5‐O1 12,82 1,46 5,57 4,64 43,81 10,99 3,79 13,92 5,74 21,48 4,95 30,03

Fp2‐F4 51,06 1,46 9,57 3,91 6,87 7,32 1,99 13,92 3,02 22,46 2,18 33,69

F4‐C4 26,58 1,46 12,67 3,91 23,57 10,99 4,29 13,92 5,31 20,02 3,22 32,23

C4‐P4 19,68 1,46 7,61 3,91 39,9 10,99 3,66 13,92 4,54 21,48 2,4 33,94

P4‐O2 23,65 1, 46 8,98 3,91 36,25 10,99 3,63 14,4 5,3 21,97 2,37 31,01

Fp1‐F3 44,22 1,46 10,29 3,91 8,51 7,32 2,71 14,16 4,01 24,41 2,78 37,11

F3‐C3 25,52 1,46 11,18 3,91 26,81 12,7 4,3 13,92 5,64 21,97 3,07 32,96

C3‐P3 17,29 1,46 7,39 3,91 46,66 10,99 3,64 14,16 5,28 21 2,59 29,79

P3‐O1 13,47 1, 46 6,11 4,15 52,96 10,99 3,7 13,92 6,07 21,48 2,59 29,79

Fz‐Cz 28,69 1,46 11,84 3,91 26,58 9,77 3,89 13,92 4, 52 19,78 2,01 32,96

Cz‐Pz 24 1, 46 10, 85 3,91 34,98 10,99 4,22 13,92 4,3 21 1,93 30,27

Average 25,64 1,46 7, 98 3,99 24,50 10,49 3,42 15,03 5, 45 22,32 4,25 32,21

Channels

GammaBeta2Beta1AlphaThetaDelta

ICHIMAT 2019 - International Conference on Health Informatics and Medical Application Technology

experiments and data processing. But overall on the

processing of data all subjects found an average

increase in alpha wave amplitude of about 20% due

to consuming soy peptides. An increase in the

average amplitude of each brain wave can be seen in

Figures 6-11. Of each wave, the most significant

increase was found in alpha waves, of course, this is

consistent with the results found in processing

individual data. However, other waves also

experienced an increase: waves: Tetha by 5.5%,

Betha 1 by 26%, Betha 2 by 33%, and Gamma by

44%, respectively. This increase does not illustrate

the dominance of increased brain activity, because

the basic amplitude is not as big as alpha waves

which is 31.2 micro volts while the base amplitude

of other waves is only less than 7 micro volts.

After processing raw data and filtering signals,

we obtain data from EEG spectra which produces a

formula resulting from the addition of brain waves

based on frequency. Figure 10 is a 2D comparison of

brain mapping based on the average power spectrum

between the before and after (5 minute and 1 hour)

comsumming soy peptide. The results show alpha

wave frequency activity is more dominant than other

wave frequencies. Alpha waves increased from the

condition of the pre-eye closure to the pre-eye

closure by 10 subjects, in subjects 10 / (S10)

experienced a significant increase from 18.46 -

67.69 uV ^ 2, from the state of fasting for ± 3 hours

until after the subject consume soybean. In the

condition of the pre-blindfold to close the eye after 1

hour after consuming soybean decreased by 5

subjects. Subject 2 / (S2) experienced a significant

decrease from 51.00 - 5.63 uV ^ 2.

Table 3: After 1 hours: Amplitude of each channels

of each brain wave.

Figure 5: Amplitude Average Comparison of Brain

Wave: Closed & Open Eyes and Pre, Pra, & After 1

Hours.

Table 4. An Average of the Brain Wave Amplitude

for All Subjcts in each Session (Pre, Pra, and After 1

Hours).

Figure 6: An Average of the Delta Apmlitude

% Hz % Hz % Hz % Hz % Hz % Hz

Fp2‐F8 32,81 1,46 8,61 3,91 7,02 7,32 2,1 13,92 3,39 24,41 2,67 32,47

F8‐T4 24,32 1,46 9,77 3,91 17,8 11,47 4,36 13,92 6,88 22,46 5,52 30,76

T4‐T6 18,97 1,46 6,79 3,91 39,08 11,47 3,06 14,16 4,39 22,22 2,2 31,25

T6‐O2 20,03 1,46 8,73 4,88 40,05 11,47 3,53 13,92 4,18 22,46 1,87 31,01

Fp1‐F7 32,2 1, 46 10,27 3,91 10,94 7,32 3,28 13,92 3,76 21,48 2,38 31,49

F7‐T3 24,91 1,46 10,69 3,91 19,23 11,47 4,5 19,78 7,14 19,78 4,66 30,03

T3‐T5 10,16 1,46 5,16 4,15 51,81 11,47 4,48 18,31 8,21 22,46 4,7 39,06

T5‐O1 9,97 1,46 7,2 3,91 61,16 11,47 3,58 13,92 5,08 22,71 2,51 30,27

Fp2‐F4 36,7 1, 46 11,4 3,91 9,52 7,32 3 15,63 4,06 20,51 2,65 32,47

F4‐C4 25,79 1,46 14,18 5,37 27,74 11,47 5,25 13,92 5,76 20,51 2,62 29,79

C4‐P4 17,35 1,46 9,05 3,91 48,72 11,47 4,12 13,92 4,75 22,46 1,76 31,01

P4‐O2 15,46 1,46 9,48 3,91 49,42 11,47 4,23 13,92 6 22,46 2,09 31,01

Fp1‐F3 36,8 1,46 11,27 3,91 9,35 7,32 3,11 14,65 3,73 21 2,08 29,79

F3‐C3 23,41 1,46 13,34 6 ,1 31,57 11,96 4,61 13,92 5,73 20,51 2,42 30,27

C3‐P3 14,76 1,46 7,18 3,91 54,28 11,47 3,74 13,92 5,36 23,19 1,66 30,27

P3‐O1 10,81 1,46 7,41 6,35 60,02 11,47 3,76 14,16 5,29 21,73 1,73 30,27

Fz‐Cz 22,97 1,46 13,16 6,1 24,38 11,96 4,06 13,92 4,84 19,78 2,68 30,03

Cz‐Pz 15,24 1,46 9,54 5,62 52 11,47 4,44 13,92 5,13 20,51 1,97 31,49

Average 21,81 1,46 9,62 4,53 34,12 10,60 3,85 14,65 5,20 21,70 2,68 31,26

Channels

Delta Theta A lpha Beta1 Beta2 Gamma

δθαβ1 β2 γδ θ αβ1 β2 γδ θ αβ1 β2 γ

S1 21,9 7,9 26,8 8,5 6,6 4,1 16,2 7,4 31,0 9,9 8,2 6,0 21,2 8,9 20,3 8,0 6,2 2,8

S2 23,5 8,1 14,7 3,3 4,4 2,4 16,4 7,1 19,9 5,5 9,9 9,4 17,8 4,9 11,8 2,7 4,2 2,8

S3 21,2 7,1 33,7 3,7 4,4 1,8 20,3 6,0 27,0 2,8 3,2 0,6 17,1 8,3 32,8 4,7 5,5 2,7

S4 17,5 12,9 47,1 4,7 3,8 2,1 17,8 11,4 48,1 4,1 3,1 1,6 16,5 12,0 45,0 3,7 2,4 1,3

S5 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 14,4 5,7 11,7 7,1 7,4 7,8

S6 17,4 5,9 46,3 4,2 5,5 2,2 12,3 4,4 42,3 3,2 4,7 1,9 10,2 5,6 54,8 5,6 8,5 4,0

S7 19,5 7,0 29,1 3,8 5,0 3,2 17,3 6,4 35,4 4,2 5,8 3,9 14,4 5,6 36,5 4,3 5,7 3,3

S8 13,5 7,7 44,6 7,0 6,8 3,9 15,1 7,6 39,2 7,2 7,6 4,9 13,6 8,3 45,3 6,6 6,3 3,4

S9 10,6 7,2 63,8 4,4 3,6 1,9 10,7 7,4 62,1 3,7 3,1 1,7 10,2 5,5 57,3 3,8 3,3 2,0

S10 14,7 13,7 55,8 3,3 2,5 1,4 15,5 13,6 51,6 3,4 3,2 2,0 13,6 14,4 57,2 3,3 2,4 1,2

S11 25,6 8,0 24,5 3,4 5,4 4,2 23,4 9,0 31,1 3,5 5,0 2,7 21,8 9,6 34,1 3,8 5,2 2,7

S12 16,1 6,0 42,6 5,6 5,7 3,0 16,4 7,2 42,6 6,2 6,3 3,8 15,6 5,2 29,1 4,5 4,7 2,9

S13 14,6 9,1 35,7 4,4 7,8 3,7 12,0 6,4 24,0 3,3 5,7 2,9 13,7 7,7 28,8 3,8 6,6 1,7

S14 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 15,7 5,9 36,0 7,1 9,3 6,1

S15 18,2 13,6 34,0 4,7 6,2 4,3 17,3 12,2 38,3 4,7 6,1 4,4 14,0 9,8 39,9 5,3 6,8 5,6

S16 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 0,0 8,8 4,8 45,9 4,3 8,5 7,3

S17 21,7 9,2 31,9 3,6 3,8 3,6 20,6 7,4 25,1 2,3 2,1 2,0 18,3 9,1 36,6 3,5 3,1 3,3

Av.

15,1 7,3 31,2 3,8 4,2 2,5 13,6 6,7 30,5 3,8 4,3 2,8 15,1 7,7 36,7 4,8 5,6 3,6

Pre Pra After 1 Hour

An Experiment for Soy Peptide Investigation Effect on Brain Wave Activity with EEG Signals

Figure 7: An Average of the Theta Apmlitude

Figure 8: An Average of the Alpha Apmlitude

Figure 9: An Average of the Beta1 Apmlitude

Figure 10: An Average of the Beta2 Apmlitude

Figure 11: An Average of the Gamma Apmlitude.

Figure 12: 2D Brain Bapping before and after

consumig soy peptide: (a) Before (b) after 5 minute,

4 CONCLUSIONS

Experiments on 17 subjects with the condition of

relaxing closed eyes to test the effect of consuming

soy peptide food on the brain have been successfully

carried out. The dominant brain activity is found in

alpha waves. An increase in alpha wave amplitude

for individuals and groups of 40% and 20%,

respectively, was obtained. Overall, it can be

concluded that consuming soy peptide food has been

shown to increase brain wave activity.

ACKNOWLEDGEMENTS

This research was supported by Technical

Implementation Unit for Instrumentation

Development, Indonesian Institute of Sciences, and

ICHIMAT 2019 - International Conference on Health Informatics and Medical Application Technology

Department of Electical Engineering, Universitas

Padjajaran, and funded by PT. Amerta Indah Otsuka,

Indonesia.

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