Enhanced Extraction of Total Polyphenols Content from Mitragyna Speciosa (Korth.) Havil Leaves using the Natural Deep Eutectic Solvent-based Microwave-assisted Extraction Method

Islamudin Ahmad, Wisnu Prabowo, Yuspian Nur, Lulu Irawan, Andi Yusniah, Bakti Rahayu, Ramila Hidayati, Hesti Nurlinda, Herman

2019

Abstract

Exploration of natural products is highly dependent on separation techniques, mainly solvent selection, one of which is using the green chemistry principle approach. Mitragyna speciosa (Koth.) Havil is an endemic plant of East Kalimantan which traditionally used for the treatment of various diseases. On the other hand, this plant has an addictive effect. The study aims to determine the impact of using natural deep eutectic solvent-based microwave-assisted extraction (NADES-MAE) on total polyphenol content (TPC) extraction from M. speciosa. Natural deep eutectic solvent (NADES) made by malting two combination types include citric acid-glucose; choline chloride-sorbitol; malic acid-glucose; and lactic acid-sucrose. The extraction process was carried out using microwave-assisted extraction (MAE), and the determination of TPC was analyzed using Folin-Ciocalteau’s reagent and measured with a spectrophotometer type including 246.70 mg GAE/g sample (citric acid-glucose), 227.33 mg GAE/g sample (malic acid-glucose), 222.26 mg GAE/g sample (lactic acid-sucrose), and 219.02 mg GAE/g sample (choline chloride-sorbitol). According to the results, the NADES-MAE method shows differences in TPC based on the NADES types.

Paper Citation

in Harvard Style

Ahmad I., Prabowo W., Nur Y., Irawan L., Yusniah A., Rahayu B., Hidayati R., Nurlinda H. and Herman. (2019). Enhanced Extraction of Total Polyphenols Content from Mitragyna Speciosa (Korth.) Havil Leaves using the Natural Deep Eutectic Solvent-based Microwave-assisted Extraction Method.In Proceedings of the 1st International Conference on Health - Volume 1: ICOH, ISBN 978-989-758-454-1, pages 72-77. DOI: 10.5220/0009564500720077

in Bibtex Style

@conference{icoh19,
author={Islamudin Ahmad and Wisnu Prabowo and Yuspian Nur and Lulu Irawan and Andi Yusniah and Bakti Rahayu and Ramila Hidayati and Hesti Nurlinda and Herman},
title={Enhanced Extraction of Total Polyphenols Content from Mitragyna Speciosa (Korth.) Havil Leaves using the Natural Deep Eutectic Solvent-based Microwave-assisted Extraction Method},
booktitle={Proceedings of the 1st International Conference on Health - Volume 1: ICOH,},
year={2019},
pages={72-77},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009564500720077},
isbn={978-989-758-454-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health - Volume 1: ICOH,
TI - Enhanced Extraction of Total Polyphenols Content from Mitragyna Speciosa (Korth.) Havil Leaves using the Natural Deep Eutectic Solvent-based Microwave-assisted Extraction Method
SN - 978-989-758-454-1
AU - Ahmad I.
AU - Prabowo W.
AU - Nur Y.
AU - Irawan L.
AU - Yusniah A.
AU - Rahayu B.
AU - Hidayati R.
AU - Nurlinda H.
AU - Herman.
PY - 2019
SP - 72
EP - 77
DO - 10.5220/0009564500720077