The Effect of Ginger (Zingiber Officinale Roscoe) Fractionation in Decreasing Uric Acid Level of Hyperuricemic White Mice

Tika Afriani, Rizky Yulion, Marlina Andriani, Fahma Syufyani, Darma Fadri

2019

Abstract

This study aims to determine the effects of ginger fractionation on uric acid level of hyperuricemic white mice. The study was conducted in 7 days using an in vivo experimental method. Ginger was extracted with 70% ethanol and subsequently fractionated by using n-hexane, ethyl acetate, and water residual solvents. The mice divided into six group treatments. Doses used of the fraction n-hexane, ethyl acetate, and water residual were 100 mg/kg of body weight and allopurinol as a standard was 10 mg/kg of body weight. The examination was carried out on mice with hyperuricemic induced by fresh chicken liver juice 0.5 ml/20g of body weight administered orally. The uric acid levels were measured by NESCO® Multi Check Digital tools. The result of this study showed that ethyl acetate fraction doses 100 mg/kg of body weight are the best fraction to lowering level of uric acid in blood serum.

Paper Citation

in Harvard Style

Afriani T., Yulion R., Andriani M., Syufyani F. and Fadri D. (2019). The Effect of Ginger (Zingiber Officinale Roscoe) Fractionation in Decreasing Uric Acid Level of Hyperuricemic White Mice.In Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT, ISBN 978-989-758-460-2, pages 467-474. DOI: 10.5220/0009838404670474

in Bibtex Style

@conference{ichimat19,
author={Tika Afriani and Rizky Yulion and Marlina Andriani and Fahma Syufyani and Darma Fadri},
title={The Effect of Ginger (Zingiber Officinale Roscoe) Fractionation in Decreasing Uric Acid Level of Hyperuricemic White Mice},
booktitle={Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,},
year={2019},
pages={467-474},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009838404670474},
isbn={978-989-758-460-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,
TI - The Effect of Ginger (Zingiber Officinale Roscoe) Fractionation in Decreasing Uric Acid Level of Hyperuricemic White Mice
SN - 978-989-758-460-2
AU - Afriani T.
AU - Yulion R.
AU - Andriani M.
AU - Syufyani F.
AU - Fadri D.
PY - 2019
SP - 467
EP - 474
DO - 10.5220/0009838404670474