Comparison of Serum MMP-1 Value Levels in Spondylitis Tuberculose with Degenerative Spine Disease

Alamsyah Faritz Siregar, Otman Siregar, Nazar Moesbar

2019

Abstract

The purpose of this study was to determine differences in serum MMP-1 values in tuberculous spondylitis with degenerative diseases of the spine. Eighteen (18) subjects were divided into 2 groups, with nine (9) subjects of spondylitis tuberculose and 9 subjects of degenerative spine disease in the period from December 2017 to November 2018 who were included in the inclusion criteria included in this study and blood sampling was taken for examination of serum MMP-1 levels. Distribution of samples of spondylitis tuberculous and degenerative spine diseases with total 18 subjects, with 10 women (55.6%) and men as many as 8 subjects (44.4%), with the youngest age of the study subject 13 years old and the oldest age is 73 years old research subjects with mean and standard deviation of 43.72 ± 15.88 years. There were significant differences in serum MMP-1 levels between spondylitis tuberculous and degenerative spine diseases with a significance value of 0.016 (p<0.05) with mean serum MMP-1 levels in the spondylitis tuberculous study group 1055.56 ± 390.86 and mean in the control group 666.67 ± 250.00. Patients suffering from spondylitis tuberculous have higher serum MMP-1 levels than patients with degenerative spine disease, although MMP-1 is not a specific marker examination for spondylitis tuberculous, the results of this study can be suggestive into that can help to evaluate enzyme activity in patients with spondylitis tuberculous disease.

Paper Citation

in Harvard Style

Siregar A., Siregar O. and Moesbar N. (2019). Comparison of Serum MMP-1 Value Levels in Spondylitis Tuberculose with Degenerative Spine Disease.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 5-8. DOI: 10.5220/0009840900050008

in Bibtex Style

@conference{ictromi19,
author={Alamsyah Faritz Siregar and Otman Siregar and Nazar Moesbar},
title={Comparison of Serum MMP-1 Value Levels in Spondylitis Tuberculose with Degenerative Spine Disease},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={5-8},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009840900050008},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Comparison of Serum MMP-1 Value Levels in Spondylitis Tuberculose with Degenerative Spine Disease
SN - 978-989-758-469-5
AU - Siregar A.
AU - Siregar O.
AU - Moesbar N.
PY - 2019
SP - 5
EP - 8
DO - 10.5220/0009840900050008