Anti-inflammatory Activity Test for Ethanol Extract Moon Flower (Tithonia diversifolia) Leaves to Male White Mice

Basyariah Lubis, Ika Nur Saputri, Rony Ajartha, Sri Melda Br Bangun, Chandra Pranata, Novandi Purba, Nur Ulina M. Br. Turnip

2019

Abstract

Introduction Hibiscus leaves (Tithonia diversifolia) are wild plants. Leaves, root bark and stems of the moon are parts that can be used for traditional medicine. This research was conducted with the aim to determine the effect of ethanol extracts of the moon flower (Tithonia diversifolia) as an anti-inflammatory Methods. The method used was artificial edema of white male male foot mice with 1% carrageenan induction of 0.05 ml as an edema maker and as a positive control using Na-Diclofenac. This research was a kind of pure experimental research. Data obtained to find the percentage of inflammation inhibition power. Data distribution was analyzed by the Kolmogorov-Smirnov test, followed by the ANOVA test and the LSD test with a confidence level of 95%. The research results showed that lunar leaves have an anti-inflammatory effect expressed by the% inhibitory inflammation at the lowest dose of 50 mg / kg bw followed by 100 mg / kg bw and 150 mg / kg bw have the highest percentage of inflammation inhibition. In the ANOVA test showed a significant difference in each treatment group at the hours of 1 to 6 hours significantly different at the test level (α ≤ 0.05). Discussion was expected to be able to identify the potential antioxidant activity of the leaves of the moon flower (Tithonia diversifolia) by chromatography.

Paper Citation

in Harvard Style

Lubis B., Saputri I., Ajartha R., Bangun S., Pranata C., Purba N. and Turnip N. (2019). Anti-inflammatory Activity Test for Ethanol Extract Moon Flower (Tithonia diversifolia) Leaves to Male White Mice.In Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT, ISBN 978-989-758-460-2, pages 551-557. DOI: 10.5220/0009974705510557

in Bibtex Style

@conference{ichimat19,
author={Basyariah Lubis and Ika Nur Saputri and Rony Ajartha and Sri Melda Br Bangun and Chandra Pranata and Novandi Purba and Nur Ulina M. Br. Turnip},
title={Anti-inflammatory Activity Test for Ethanol Extract Moon Flower (Tithonia diversifolia) Leaves to Male White Mice},
booktitle={Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,},
year={2019},
pages={551-557},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009974705510557},
isbn={978-989-758-460-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference on Health Informatics and Medical Application Technology - Volume 1: ICHIMAT,
TI - Anti-inflammatory Activity Test for Ethanol Extract Moon Flower (Tithonia diversifolia) Leaves to Male White Mice
SN - 978-989-758-460-2
AU - Lubis B.
AU - Saputri I.
AU - Ajartha R.
AU - Bangun S.
AU - Pranata C.
AU - Purba N.
AU - Turnip N.
PY - 2019
SP - 551
EP - 557
DO - 10.5220/0009974705510557