Lupus Erythematosus Panniculitis: Clinical and Histopathological Diagnostic Challenge

Vashty Amanda Hosfiar, Agung M. Rheza, Sondang P. Sirait, Eyleny Meisyah Fitri, Rahadi Rihatmadja, Endi Novianto

2019

Abstract

Panniculitis is the inflammation of subcutaneous fatthat sometimesassociated with connective tissue diseases.One of the well-described forms of connective tissue panniculitis is lupus erythematosus panniculitis (LEP). We report a 35-year-old female patient with skin atrophic lesions on the lateral aspect of the upper arms and cheeks for at least 8-year duration. The atrophic lesions were followed by recurrent multiple small nodules on the right jaw and neck, on which excisional biopsy was performed. Histopathologyexamination revealed lobular panniculitis consistent with LEP. However, slight hyalinosis and thickened collagen bundles were also observed that deep morphea could not be ruled out. The patient was treated with hydroxychloroquine 200 mg/day and methotrexate 7.5 mg a week, showing improvement by decreased ANA titer. No new nodules and enlargement of atrophic areas were found after the one-month course of therapy.

Paper Citation

in Harvard Style

Hosfiar V., Rheza A., Sirait S., Fitri E., Rihatmadja R. and Novianto E. (2019). Lupus Erythematosus Panniculitis: Clinical and Histopathological Diagnostic Challenge.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 272-276. DOI: 10.5220/0009986402720276

in Bibtex Style

@conference{ictromi19,
author={Vashty Amanda Hosfiar and Agung M. Rheza and Sondang P. Sirait and Eyleny Meisyah Fitri and Rahadi Rihatmadja and Endi Novianto},
title={Lupus Erythematosus Panniculitis: Clinical and Histopathological Diagnostic Challenge},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={272-276},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009986402720276},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Lupus Erythematosus Panniculitis: Clinical and Histopathological Diagnostic Challenge
SN - 978-989-758-469-5
AU - Hosfiar V.
AU - Rheza A.
AU - Sirait S.
AU - Fitri E.
AU - Rihatmadja R.
AU - Novianto E.
PY - 2019
SP - 272
EP - 276
DO - 10.5220/0009986402720276