Diagnosing Leprosy in Infants: A Histopathological Challenge using Several Staining Technique

Joanne Natasha, Rizky L. Prayogo, Michael H. Angriawan, Rinadewi Astriningrum, Melani Marissa, Sri Linuwih Menaldi, Sondang P. Sirait

2019

Abstract

Leprosy in infants is a rare case compared to adults. There is an excellent variety of the clinical cutaneous finding in leprosy.Leprosy diagnostic is based on the classical cardinal signs, the presence of acid-fast bacilli which is obtained by slit skin smear and skin biopsy. The gold standard to diagnose leprosy is the identification of Mycobacterium leprae (M. leprae) bacilli using Hematoxylin and Eosin (H&E) and Fite Faraco (FF) stains. Periodic acid-Schiff (PAS) and Gomori (Grocott) methenamine-silver (GMS), known to give the positive result for fungal staining, revealed the other function is becoming the alternative staining for M. leprae. Hereby, we report a case of a six-month-old male patient who presented unusual clinical findings that were never considered asleprosy initially. Histopathological examination with several stains was performed, and a diagnosis of lepromatous leprosy was obtained.

Paper Citation

in Harvard Style

Natasha J., Prayogo R., Angriawan M., Astriningrum R., Marissa M., Menaldi S. and Sirait S. (2019). Diagnosing Leprosy in Infants: A Histopathological Challenge using Several Staining Technique.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 290-294. DOI: 10.5220/0009987002900294

in Bibtex Style

@conference{ictromi19,
author={Joanne Natasha and Rizky L. Prayogo and Michael H. Angriawan and Rinadewi Astriningrum and Melani Marissa and Sri Linuwih Menaldi and Sondang P. Sirait},
title={Diagnosing Leprosy in Infants: A Histopathological Challenge using Several Staining Technique},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={290-294},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009987002900294},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Diagnosing Leprosy in Infants: A Histopathological Challenge using Several Staining Technique
SN - 978-989-758-469-5
AU - Natasha J.
AU - Prayogo R.
AU - Angriawan M.
AU - Astriningrum R.
AU - Marissa M.
AU - Menaldi S.
AU - Sirait S.
PY - 2019
SP - 290
EP - 294
DO - 10.5220/0009987002900294