A Very Rare Case of De Novo Histoid Leprosy with Type 1 Reaction

Aninda Marina, Sondang P. Sirait, Sri Linuwih Menaldi

2019

Abstract

Histoid leprosy (HL) is a distinct and rare type of leprosy with unique clinical manifestations and specific histopathology of multibacillary leprosy (MB). Histoid leprosy generally occurs in lepromatous leprosy patients (LL) or borderline lepromatous (BL). Often it occurs after inadequate dapsone treatment despite sometimes arise de novo as well. Histoid forms can ensue accompanied by reactions of erythema nodosum leprosum (ENL) and rarely reversal reactions. Diagnosis of HL based on clinical manifestations, bacteriological examination, and histopathological examination. Clinical manifestations are typical such as coppery nodules, well-defined, might be soft or hard, shiny, with varying sizes. Histopathological findings showed a longitudinal or spindle histiocyte containing M. leprae. We report a rare case of histoid leprosy accompanied by reversal reactions. A 59-year-old Chinese woman, from West Borneo, complained of a painless nodule on the face and body since two months ago with swollen face and rashes. Patients never had leprosy treatment before Histopathological shows some spindle cells. Patients are diagnosed with histoid leprosy and reversal reactions. Diagnosis of histoid leprosy is made by history, physical examination, and histopathology. Patients fall into the de novo category due to having never been treated with dapsone before. The therapy given to patients is multibacillary multi drugs therapy (MDT-MB) and corticosteroids. The patient showed improvement in lesions after six months of MDT-MB and corticosteroids for three months. Histoid leprosy is able to occur de novo and accompanied by reversal reactions. Early diagnosis and complete treatment are crucial to achieve the goal of elimination of leprosy.

Paper Citation

in Harvard Style

Marina A., Sirait S. and Menaldi S. (2019). A Very Rare Case of De Novo Histoid Leprosy with Type 1 Reaction.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 312-315. DOI: 10.5220/0009987603120315

in Bibtex Style

@conference{ictromi19,
author={Aninda Marina and Sondang P. Sirait and Sri Linuwih Menaldi},
title={A Very Rare Case of De Novo Histoid Leprosy with Type 1 Reaction},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={312-315},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009987603120315},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - A Very Rare Case of De Novo Histoid Leprosy with Type 1 Reaction
SN - 978-989-758-469-5
AU - Marina A.
AU - Sirait S.
AU - Menaldi S.
PY - 2019
SP - 312
EP - 315
DO - 10.5220/0009987603120315