A Case Report: Psoriasis-mimicking Lesions of Secondary Syphilis in HIV Positive Patient

Vika Fintaru, Sunardi Radiono, Satiti Retno Pudjiati

2019

Abstract

Syphilis is a sexually transmitted disease that is considered to be "the great imitator" because of the clinical appearance that resembles various types of skin diseases. The coincidence between syphilis and Human Immunodeficiency Virus(HIV) often occurs, and the incidence increases, especially in the male population who have sex with men. Uncommon syphilis clinical manifestations are common in HIV patients. This paper reports a 28-year-old man who was infected with HIV, came to Dr. Sardjito General Hospital's Dermatovenereology polyclinic, with a complaint of scaly red plaques on the arms, legs, hands, feet, and scrotum and accompanied by nail abnormalities that mimicking skin and nail abnormalities in psoriasis. Histopathology examination appropriate with secondary syphilis with psoriasiform acanthosis, neither hypergranulosis nor Monroe abscess, and many lymphocytes and plasma cells infiltration in the upper dermis, perivascular, and periadnexa. The serological test showed a positive result of Treponema Pallidum Haemagglutination (TPHA) and Venereal Disease Research Laboratory (VDRL) 1/32. The patient was treated with injections of benzathine penicillin G 2.4 million units single dose. Skin and nail lesions improvement occurred three months after therapy. Variable clinical presentations of secondary syphilis in HIV disease may lead to wrong diagnosis and improper treatment. The biopsy can be used to make a diagnosis of atypical syphilis lesions. Syphilis patients with HIV infectionmore likely to experience serological declinefailure, recurrent infections, and slower treatment response than patients who are not infected with HIV.

Paper Citation

in Harvard Style

Fintaru V., Radiono S. and Pudjiati S. (2019). A Case Report: Psoriasis-mimicking Lesions of Secondary Syphilis in HIV Positive Patient.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 333-337. DOI: 10.5220/0009988103330337

in Bibtex Style

@conference{ictromi19,
author={Vika Fintaru and Sunardi Radiono and Satiti Retno Pudjiati},
title={A Case Report: Psoriasis-mimicking Lesions of Secondary Syphilis in HIV Positive Patient},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={333-337},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009988103330337},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - A Case Report: Psoriasis-mimicking Lesions of Secondary Syphilis in HIV Positive Patient
SN - 978-989-758-469-5
AU - Fintaru V.
AU - Radiono S.
AU - Pudjiati S.
PY - 2019
SP - 333
EP - 337
DO - 10.5220/0009988103330337