Single Case Report: Diffuse Cutaneous Mastocytosis with Generalized Bullae Mimicking Bullous Pemphigoid

Muhammad Ridlo, Irma D. Roesyanto Mahadi, Remenda Siregar

2019

Abstract

Introduction:Mastocytosisis a rare disease; it is defined as mast cells infiltration in some organs. Skin is the most commonly involved organ.Diffuse cutaneous mastocytosisis a form of skin mastocytosiswhich can be manifested as bullous lesions. Case: A 3-month-old male infant is presentedwith generalized dermatosis, characterized by multipleblisters and brownish spots all over his bodysince one month ago.On dermatologic examination, multiple tense bullae of various sizes with brownmacules and plaques are located throughout the body.Some bullae rupture to form an erosion.Darier sign showserythema/mild urticaria lesions(positive). Routine blood tests within normal limits. The histopathologic examination reveals sub-epidermal bullae with aninflammatory cell and the dermis is filled with inflammatory cells and mast cells. Patients were diagnosed with diffuse cutaneous bullous mastocytosis. The patient was treated with 0.9% NaCl compresses, 2% mupirocin cream, and 0.1% betamethasone cream. Monitoring therapy is done routinely to evaluate the prognosis of the disease.Discussion:Diffuse cutaneous bullous mastocytosis is one of the rarest forms of skin mastocytosis. Cutaneous mastocytosis in children who persist until adolescence develops systemic mastocytosis in 15-30% cases so early diagnosis of mastocytosis in children is very important to get a goodprognosis. Conclusion: Diagnosisdiffuse cutaneous mastocytosis is not easy because the prevalence is difficult to determine and often misdiagnosed. Here,we report this case due to the similarity clinical manifestation of bullous diseases, especially in a newborn with scattered blisters and erosions.

Paper Citation

in Harvard Style

Ridlo M., Mahadi I. and Siregar R. (2019). Single Case Report: Diffuse Cutaneous Mastocytosis with Generalized Bullae Mimicking Bullous Pemphigoid.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 436-440. DOI: 10.5220/0009991004360440

in Bibtex Style

@conference{ictromi19,
author={Muhammad Ridlo and Irma D. Roesyanto Mahadi and Remenda Siregar},
title={Single Case Report: Diffuse Cutaneous Mastocytosis with Generalized Bullae Mimicking Bullous Pemphigoid},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={436-440},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009991004360440},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Single Case Report: Diffuse Cutaneous Mastocytosis with Generalized Bullae Mimicking Bullous Pemphigoid
SN - 978-989-758-469-5
AU - Ridlo M.
AU - Mahadi I.
AU - Siregar R.
PY - 2019
SP - 436
EP - 440
DO - 10.5220/0009991004360440