Antimicrobial Potential Activity of Extract Selaginella plana (Desv. Ex Poir.) Hieron against the Growth of Staphylococcus aureus ATCC 25922 and Methicillin-Resistance Staphylococcus aureus (MRSA)

Juen Carla Warella, Agung Dwi Wahyu Widodo, Rebekah Juniati Setiabudi, Retno Indrawati Roestamadji, Maftuchah Rochmanti, Pudji Lestari

2020

Abstract

For thousands years, medicinal plants have been used as a source of powerful therapeutic agents, and until now, many medicines are used from natural products derived from plants or their derivatives. Plants that contain secondary metabolites can be used as antimicrobials, one of them is Selaginella plana. In this study, there were 8 treatments consisting of 6 treatments of extract concentration, 1 positive control (vancomycin), and 1 negative control (distilled water) with 3 replications. The antimicrobial test used was the Tube Dilution method using Mueller Hinton Broth to determine the MIC and Mueller Hinton Agar to determine the MBC. Selaginella plana extract showed inhibition against Staphylococcus aureus with MIC values of 12.5% and in MRSA with MIC value of 50%. In MBC test, the killing power of Selaginella plana extract against Staphylococcus aureus obtained MBC value of 12.5%. Meanwhile, MRSA bacteria showed negative results, which were indicated by the growth of colonies. Selaginella plana extract (Desv.ex Poir.) Hieron was able to show antimicrobial activity on Staphylococcus aureus with the MIC value of 12.5%, and the MBC value of 12.5% while in MRSA, Selaginella plana extract (Desv.ex Poir.) Hieron had an MIC value of 50 %, and the MBC value was negative.

Paper Citation

in Harvard Style

Warella J., Wahyu Widodo A., Setiabudi R., Roestamadji R., Rochmanti M. and Lestari P. (2020). Antimicrobial Potential Activity of Extract Selaginella plana (Desv. Ex Poir.) Hieron against the Growth of Staphylococcus aureus ATCC 25922 and Methicillin-Resistance Staphylococcus aureus (MRSA).In Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia - Volume 1: JIMC, ISBN 978-989-758-499-2, pages 245-253. DOI: 10.5220/0010490802450253

in Bibtex Style

@conference{jimc20,
author={Juen Carla Warella and Agung Dwi Wahyu Widodo and Rebekah Juniati Setiabudi and Retno Indrawati Roestamadji and Maftuchah Rochmanti and Pudji Lestari},
title={Antimicrobial Potential Activity of Extract Selaginella plana (Desv. Ex Poir.) Hieron against the Growth of Staphylococcus aureus ATCC 25922 and Methicillin-Resistance Staphylococcus aureus (MRSA)},
booktitle={Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia - Volume 1: JIMC,},
year={2020},
pages={245-253},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010490802450253},
isbn={978-989-758-499-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia - Volume 1: JIMC,
TI - Antimicrobial Potential Activity of Extract Selaginella plana (Desv. Ex Poir.) Hieron against the Growth of Staphylococcus aureus ATCC 25922 and Methicillin-Resistance Staphylococcus aureus (MRSA)
SN - 978-989-758-499-2
AU - Warella J.
AU - Wahyu Widodo A.
AU - Setiabudi R.
AU - Roestamadji R.
AU - Rochmanti M.
AU - Lestari P.
PY - 2020
SP - 245
EP - 253
DO - 10.5220/0010490802450253