Blood Transfusion, Serum Total Iron Binding Capacity and Iron in Hemodialysis Patients Margono Soekarjo Hospital

Vitasari Indriani, Aditiawarman, Yunanto Dwi Nugroho, Fania Salsabila

2020

Abstract

In the final stages, chronic kidney disease (CKD) patients require renal replacement therapy like hemodialysis (HD). Packed Red Cell (PRC) transfusion is an anaemia management therapy that can increase serum Total Iron Binding Capacity (TIBC) and iron levels. This study analyzed blood transfusions, TIBC serum and iron serum levels in hemodialysis patients with repeated transfusions at Margono Soekarjo Hospital to assess the value of TIBC in the iron excess and deficiency diagnosis. An observational analytic design with cross-sectional findings was used. We investigated 85 hemodialysis patients; (73.3% men and 26.7% women aged 20 to 70 years) visited hemodialysis clinics from January 2018 to 2020. Correlation studies showed a linear relationship between the number of blood transfusions and the level of iron serum in hemodialysis patients (value 𝑃: 0.0001), a positive correlation between the number of blood transfusions and TIBC serum concentration (value 𝑃: 0.04); the significant relationship between TIBC serum and iron serum (value: 0.003). The prevalence of excess iron was 10.6%, and 2.3% in iron deficiency. Non-iron therapy patients with a maximum of one transfusion with iron therapy, patients with transfusions who are not on iron therapy, and patients on oral iron therapy were compared. The Kruskal-Wallis test showed that iron levels varied significantly between groups (𝑃 value: 0.0001). TIBC serum is not a reliable marker of excess iron. For patients with regular transfusions, periodical checking of TIBC and iron serum is recommended.

Paper Citation

in Harvard Style

Indriani V., Aditiawarman., Nugroho Y. and Salsabila F. (2020). Blood Transfusion, Serum Total Iron Binding Capacity and Iron in Hemodialysis Patients Margono Soekarjo Hospital.In Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia - Volume 1: JIMC, ISBN 978-989-758-499-2, pages 284-288. DOI: 10.5220/0010491502840288

in Bibtex Style

@conference{jimc20,
author={Vitasari Indriani and Aditiawarman and Yunanto Dwi Nugroho and Fania Salsabila},
title={Blood Transfusion, Serum Total Iron Binding Capacity and Iron in Hemodialysis Patients Margono Soekarjo Hospital},
booktitle={Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia - Volume 1: JIMC,},
year={2020},
pages={284-288},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010491502840288},
isbn={978-989-758-499-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st Jenderal Soedirman International Medical Conference in conjunction with the 5th Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia - Volume 1: JIMC,
TI - Blood Transfusion, Serum Total Iron Binding Capacity and Iron in Hemodialysis Patients Margono Soekarjo Hospital
SN - 978-989-758-499-2
AU - Indriani V.
AU - Aditiawarman.
AU - Nugroho Y.
AU - Salsabila F.
PY - 2020
SP - 284
EP - 288
DO - 10.5220/0010491502840288