Analysis of the Use of Colour for Early Detection of Dementia

Thomas Ostermann, Sibylle Robens, Petra Heymann, Sebastian Unger, Stephan Müller, Christoph Laske, Ulrich Elbing

2020

Abstract

Cognitive visuo-constructive impairments, which can be detected by drawing tasks are early signs of Alzheimer’s disease (AD). Additionally, several studies revealed deficits in colour perception for patients with AD. In a former analysis of the impact of digital tree-drawing parameters on the screening of early dementia, a logistic regression revealed the number of colours together with the drawing velocity and the number of line widths changes as discrimination characteristics (ROC AUC=0.90, sensitivity=.86, specificity=0.82). To analyse the diagnostic importance of colour variations in drawings, a reanalysis of these data was done with 67 healthy subjects (25 females, mean age 66 ± 10 yrs.) and 56 subjects with early AD (40 females, mean age 73 ± 9 yrs.). The exclusion of colour variables resulted in a good discrimination of healthy and AD (ROC AUC=0.89, specificity=0.89) but in a reduction of sensitivity to .77 compared to the former model. This suggest that the analysis of colour variations in drawings has an important diagnostic impact.

Paper Citation

in Harvard Style

Ostermann T., Robens S., Heymann P., Unger S., Müller S., Laske C. and Elbing U. (2020). Analysis of the Use of Colour for Early Detection of Dementia. In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 5: HEALTHINF; ISBN 978-989-758-398-8, SciTePress, pages 316-320. DOI: 10.5220/0008881303160320

in Bibtex Style

@conference{healthinf20,
author={Thomas Ostermann and Sibylle Robens and Petra Heymann and Sebastian Unger and Stephan Müller and Christoph Laske and Ulrich Elbing},
title={Analysis of the Use of Colour for Early Detection of Dementia},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 5: HEALTHINF},
year={2020},
pages={316-320},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008881303160320},
isbn={978-989-758-398-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 5: HEALTHINF
TI - Analysis of the Use of Colour for Early Detection of Dementia
SN - 978-989-758-398-8
AU - Ostermann T.
AU - Robens S.
AU - Heymann P.
AU - Unger S.
AU - Müller S.
AU - Laske C.
AU - Elbing U.
PY - 2020
SP - 316
EP - 320
DO - 10.5220/0008881303160320
PB - SciTePress