Xtrace: Novel Bioresorbable Device for Patent Foramen Ovale Closure

Sara Abu Ajamieh, Diana Mindroc-Filimon, Irene Mozo, Isabel Rocha

2020

Abstract

Patent foramen ovale (PFO) is a congenital cardiac lesion, affecting about 25% to 30% of the adult population. It is associated with several serious complications, including cryptogenic strokes, transient ischemic attacks, and migraine. The prevalence of PFO has significantly increased in patients with cryptogenic stroke; up to 40% of ischemic strokes with an unknown cause have a PFO. Recently, technical advancements in medical engineering have made the percutaneous transcatheter closure of PFO a feasible treatment option. However, current PFO closure devices may lead to complications such as the need for replacing the device after several years, sudden migration of the implant, erosion, infection, or arrhythmias. Attempts are needed to produce a safer and more effective closure devices. Here, we propose an innovative medical device called Xtrace. It consists of a biodegradable material that will be partially degraded by the host body while substituted by autologous host tissue. This innovative device will potentially fulfill the essential unmet clinical need, as well as provide a safe and effective delivery of therapy for the general population.

Paper Citation

in Harvard Style

Ajamieh S., Mindroc-Filimon D., Mozo I. and Rocha I. (2020). Xtrace: Novel Bioresorbable Device for Patent Foramen Ovale Closure. In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: ClinMed, ISBN 978-989-758-398-8, pages 344-349. DOI: 10.5220/0009374603440349

in Bibtex Style

@conference{clinmed20,
author={Sara Ajamieh and Diana Mindroc-Filimon and Irene Mozo and Isabel Rocha},
title={Xtrace: Novel Bioresorbable Device for Patent Foramen Ovale Closure},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: ClinMed,},
year={2020},
pages={344-349},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009374603440349},
isbn={978-989-758-398-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: ClinMed,
TI - Xtrace: Novel Bioresorbable Device for Patent Foramen Ovale Closure
SN - 978-989-758-398-8
AU - Ajamieh S.
AU - Mindroc-Filimon D.
AU - Mozo I.
AU - Rocha I.
PY - 2020
SP - 344
EP - 349
DO - 10.5220/0009374603440349