Adopting CRISPR-mediated Genomic Editing Technique on the Treatment of Lung Cancer: Using Revolutionary Genomic Editing Technique to Treat Serious Human Disease

Sixian Chen

2021

Abstract

CRISPR system was first discovered in E. coli in 1987 by Japanese scientist Yoshizumi Ishino and his team. Since its emergence, it has been widely applied for a variety of medical use, including lung cancer. Traditional treatments of lung cancer gradually lost in their effectiveness by inducing drug resitance. Therefore, more influencing and innovative technologies are needed urgently, and CRISPR-mediated genomic editing technique is one of them. CRISPR system helps scientist to construct tumor model, to identify certain lung cancer related genes as well as deleting or repairing those cancer genes which can be done by targeting specific genes and either inhibit or activate its function. The applications of CRISPR system are now developed in a flying speed that it already moves to the clinical testing stage. Ideally, within a decade, the adoption of CRISPR system on treating lung cancer can be popularized widely. This review summarizes the characteristics of lung cancer and the application of CRISPR system on treating lung cancer. Potential target genes related with lung cancer will be discussed including EFGR, EML4 fusion gene, TSLC1 etc. The application of CRISPR system on deleting various types of cancer gene will be introduced, too. In order to generalize CRISPR technology into human cases, more in-depth investigations of the usage of this system are necessary for future studies.

Paper Citation

in Harvard Style

Chen S. (2021). Adopting CRISPR-mediated Genomic Editing Technique on the Treatment of Lung Cancer: Using Revolutionary Genomic Editing Technique to Treat Serious Human Disease. In Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH, ISBN 978-989-758-594-4, pages 168-174. DOI: 10.5220/0011228700003444

in Bibtex Style

@conference{caih21,
author={Sixian Chen},
title={Adopting CRISPR-mediated Genomic Editing Technique on the Treatment of Lung Cancer: Using Revolutionary Genomic Editing Technique to Treat Serious Human Disease},
booktitle={Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,},
year={2021},
pages={168-174},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011228700003444},
isbn={978-989-758-594-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,
TI - Adopting CRISPR-mediated Genomic Editing Technique on the Treatment of Lung Cancer: Using Revolutionary Genomic Editing Technique to Treat Serious Human Disease
SN - 978-989-758-594-4
AU - Chen S.
PY - 2021
SP - 168
EP - 174
DO - 10.5220/0011228700003444