Lycium barbarum Polysaccharides Protects against Strenuous Exercise-induced Oxidative Damage in Rats

Lantao Liu, Weiqiang Zhang

2021

Abstract

Lycium barbarum contains a variety of nutrients and bioactive ingredients, which has multiple biological and pharmacological effects. In the theory of Chinese medicine, Lycium barbarum as a common Chinese herbal medicine can be used for the treatment of many diseases. The aim of the current study was to evaluate the protective effects of Lycium barbarum polysaccharides (LBPs) on strenuous exercise-induced oxidative damage in rats. The animals were divided into one control group (treated with distilled water) and three LBPs groups (treated with 50, 100 and 200 mg/kg LBPs, respectively). After 28 days of treatment, the exhaustive running exercise was performed, followed by the relevant biochemical parameter analysis. the datas revealed that LBPs increases exhaustive running times, and levels of superoxide dismutase (SOD), glutathione peroxidase (GPx), reduced glutathione (GSH), glutathione reductase (GR), and catalase (CAT) in liver. LBPs decreases the levels of creatine kinase (CK), myoglobin (Mb), tumor necrosis factor-α (TNF-α) and interleukin 1β (IL-1β) in serum, and also the levels of oxidized glutathione (GSSG), malondialdehyde (MDA) and 8-hydroxy-2’-deoxyguanosine (8-OHdG) in liver. These results suggest that LBPs has protective effects on oxidative damage induced by strenuous exercise.

Paper Citation

in Harvard Style

Liu L. and Zhang W. (2021). Lycium barbarum Polysaccharides Protects against Strenuous Exercise-induced Oxidative Damage in Rats. In Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH, ISBN 978-989-758-594-4, pages 255-260. DOI: 10.5220/0011316100003444

in Bibtex Style

@conference{caih21,
author={Lantao Liu and Weiqiang Zhang},
title={Lycium barbarum Polysaccharides Protects against Strenuous Exercise-induced Oxidative Damage in Rats},
booktitle={Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,},
year={2021},
pages={255-260},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011316100003444},
isbn={978-989-758-594-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Conference on Artificial Intelligence and Healthcare - Volume 1: CAIH,
TI - Lycium barbarum Polysaccharides Protects against Strenuous Exercise-induced Oxidative Damage in Rats
SN - 978-989-758-594-4
AU - Liu L.
AU - Zhang W.
PY - 2021
SP - 255
EP - 260
DO - 10.5220/0011316100003444