Virtual Planning and Simulation of Coarctation Repair in Hypoplastic Aortic Arches: Is Fixing the Coarctation Alone Enough?

Seda Aslan, Xiaolong Liu, Qiyuan Wu, Paige Mass, Yue-Hin Loke, Narutoshi Hibino, Laura Olivieri, Axel Krieger

2022

Abstract

Coarctation of aorta (CoA) is a congenital heart disease that may coexist with transverse arch hypoplasia (TAH). Infants who suffer from both conditions are often treated only for CoA at the initial repair if the degree of TAH is diagnosed as mild. In this study, we investigated the effect of virtually repairing the CoA of three patients (n=3) who also suffer from TAH. We repaired the CoA by using virtual stents that were modeled based on descending aorta diameters of the patients. Using computational fluid dynamics (CFD) simulations, we investigated the changes in time-averaged wall shear stress (TAWSS) after the virtual repair and calculated the peak systolic pressure drop (PSPD), which is the indicator of the performance of the repair. The magnitude of TAWSS was reduced in the repaired CoA regions in all the patients. The PSPD was improved in two patients, remaining above 20 mmHg in one of them. There was no significant change in PSPD for one patient after the virtual repair. The results may potentially help clinicians to gain better insights into whether the CoA repair alone in patients with existing TAH is sufficient.

Paper Citation

in Bibtex Style

@conference{bioinformatics22,
author={Seda Aslan and Xiaolong Liu and Qiyuan Wu and Paige Mass and Yue-Hin Loke and Narutoshi Hibino and Laura Olivieri and Axel Krieger},
title={Virtual Planning and Simulation of Coarctation Repair in Hypoplastic Aortic Arches: Is Fixing the Coarctation Alone Enough?},
booktitle={Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - Volume 3: BIOINFORMATICS},
year={2022},
pages={138-143},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010842600003123},
isbn={978-989-758-552-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - Volume 3: BIOINFORMATICS
TI - Virtual Planning and Simulation of Coarctation Repair in Hypoplastic Aortic Arches: Is Fixing the Coarctation Alone Enough?
SN - 978-989-758-552-4
AU - Aslan S.
AU - Liu X.
AU - Wu Q.
AU - Mass P.
AU - Loke Y.
AU - Hibino N.
AU - Olivieri L.
AU - Krieger A.
PY - 2022
SP - 138
EP - 143
DO - 10.5220/0010842600003123
PB - SciTePress

in Harvard Style

Aslan S., Liu X., Wu Q., Mass P., Loke Y., Hibino N., Olivieri L. and Krieger A. (2022). Virtual Planning and Simulation of Coarctation Repair in Hypoplastic Aortic Arches: Is Fixing the Coarctation Alone Enough?. In Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2022) - Volume 3: BIOINFORMATICS; ISBN 978-989-758-552-4, SciTePress, pages 138-143. DOI: 10.5220/0010842600003123