Bias Assessment in Medical Imaging Analysis: A Case Study on Retinal OCT Image Classification

Gabriel Oliveira, Lucas David, Rafael Padilha, Ana Paula da Silva, Francine de Paula, Lucas Infante, Lucio Jorge, Patricia Xavier, Zanoni Dias

2022

Abstract

Deep learning classifiers can achieve high accuracy in many medical imaging analysis problems. However, when evaluating images from outside the training distribution — e.g., from new patients or generated by different medical equipment — their performance is often hindered, highlighting that they might have learned specific characteristics and biases of the training set and can not generalize to real-world scenarios. In this work, we discuss how Transfer Learning, the standard training technique employed in most visual medical tasks in the literature, coupled with small and poorly collected datasets, can induce the model to capture such biases and data collection artifacts. We use the classification of eye diseases from retinal OCT images as the backdrop for our discussion, evaluating several well-established convolutional neural network architectures for this problem. Our experiments showed that models can achieve high accuracy in this problem, yet when we interpret their decisions and learned features, they often pay attention to regions of the images unrelated to diseases.

Paper Citation

in Harvard Style

Oliveira G., David L., Padilha R., Paula da Silva A., de Paula F., Infante L., Jorge L., Xavier P. and Dias Z. (2022). Bias Assessment in Medical Imaging Analysis: A Case Study on Retinal OCT Image Classification. In Proceedings of the 14th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART, ISBN 978-989-758-547-0, pages 574-580. DOI: 10.5220/0010867400003116

in Bibtex Style

@conference{icaart22,
author={Gabriel Oliveira and Lucas David and Rafael Padilha and Ana Paula da Silva and Francine de Paula and Lucas Infante and Lucio Jorge and Patricia Xavier and Zanoni Dias},
title={Bias Assessment in Medical Imaging Analysis: A Case Study on Retinal OCT Image Classification},
booktitle={Proceedings of the 14th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART,},
year={2022},
pages={574-580},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010867400003116},
isbn={978-989-758-547-0},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 14th International Conference on Agents and Artificial Intelligence - Volume 3: ICAART,
TI - Bias Assessment in Medical Imaging Analysis: A Case Study on Retinal OCT Image Classification
SN - 978-989-758-547-0
AU - Oliveira G.
AU - David L.
AU - Padilha R.
AU - Paula da Silva A.
AU - de Paula F.
AU - Infante L.
AU - Jorge L.
AU - Xavier P.
AU - Dias Z.
PY - 2022
SP - 574
EP - 580
DO - 10.5220/0010867400003116