Anti-fatigue Effects of Polysaccharides from Morchella esculenta

Fuwei Yin, Lantao Liu

2022

Abstract

Fatigue has caused indirect damage to the body or a direct cause of disease, which has led to the research and development of anti-fatigue natural medicines and supplements that have become a hot spot at home and abroad. The aim of present work was to evaluate the anti-fatigue effects of polysaccharides from M. esculenta (PMe) by using a swimming exercise animal model. The mice were assigned into a normal control group and three PMe treatment groups. The treatment groups received different doses of PMe (100, 200, and 400 mg/kg) through gastric gavage once per day for 4 weeks, and normal control group received distilled water. On the last day of the experiment, the forced swimming test was performed, and fatiguerelated biochemical parameters were analyzed. The results showed that PMe significantly prolonged (p<0.05) the swimming time to exhaustion, reduced (p<0.05) the levels of lactate, urea nitrogen and malondialdehyde in serum, increased (p<0.05) the levels of non-esterfied fatty acid in serum, as well as the glycogen levels in liver and muscle. In conclusion, PMe has the anti-fatigue effects and its mechanisms might be related to the fact that PMe could reduce the production of metabolites or delay the accumulation of metabolites, attenuate protein and amino acid metabolism, and enhance fat metabolism, reduce oxidative stress and protect oxidative damage induced by exercise, and improve the energy substance storage or reduce energy substance consumption.

Paper Citation

in Harvard Style

Yin F. and Liu L. (2022). Anti-fatigue Effects of Polysaccharides from Morchella esculenta. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 132-138. DOI: 10.5220/0011191100003443

in Bibtex Style

@conference{icbeb22,
author={Fuwei Yin and Lantao Liu},
title={Anti-fatigue Effects of Polysaccharides from Morchella esculenta},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={132-138},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011191100003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - Anti-fatigue Effects of Polysaccharides from Morchella esculenta
SN - 978-989-758-595-1
AU - Yin F.
AU - Liu L.
PY - 2022
SP - 132
EP - 138
DO - 10.5220/0011191100003443