Research on Obesity Caused by Genetic Defects in Specific Populations

Zhiru Li

2022

Abstract

Obesity is caused by several factors, including diet, exercise, and the environment. However, one critical factor that many people ignore is genetic abnormality. People are aware of the fact that the amount of food ingested, and the amount of energy exerted can impact the formation of fat. Thus, obesity can be induced by mutations or diseases in genes involved in these three systems in our body. And it is necessary to study the problem of obesity caused by genetic defects. This paper focuses on 5 genetic problems to find the obesity problems and solutions caused by genetic variants. It is found that Leptin and MC4R genes can increase appetite and lead to obesity. And UCP and beta-adrenergic receptor during energy expenditure may result in reduced energy expenditure or hormonal instability in the body, both of which will contribute to obesity. The PPARy gene is essential for fat storage, and a mutation in the gene can result in an inability to store fat, which will eventually lead to significant bodily damage. By studying and compiling the literature, this research has identified the problems that arise after each genetic variation and the corresponding solutions.

Paper Citation

in Harvard Style

Li Z. (2022). Research on Obesity Caused by Genetic Defects in Specific Populations. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 212-219. DOI: 10.5220/0011196200003443

in Bibtex Style

@conference{icbeb22,
author={Zhiru Li},
title={Research on Obesity Caused by Genetic Defects in Specific Populations},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={212-219},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011196200003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - Research on Obesity Caused by Genetic Defects in Specific Populations
SN - 978-989-758-595-1
AU - Li Z.
PY - 2022
SP - 212
EP - 219
DO - 10.5220/0011196200003443