Potentials of the Dry Granulation by Roller Compaction

Yujie Zhang

2022

Abstract

The latest trends in the field of pharmaceutical engineering are regarding roller compaction. Roller compaction technology is a well-established strategy particularly involved in the medical industry. This developing process has a great impact on the manufacturing of oral solid dosage forms while containing high-quality active pharmaceutical ingredients (API). When the medical industry tends to develop a tablet, there are three basic processing routes that have been considered: direct compression, dry granulation, and wet granulation. Among these three high-efficiency productive ways, dry granulation is a process that compresses powdery ingredients into tablets without adding any liquid solution. Dry granulation is carried out using either slugging or roller compaction techniques. This pharmaceutic process has potentials for drug development as it has been proved to continuously manufacture tablets by working with compaction machines. Roller compaction employed to dry granulation can provide more advantages compared with other processing methods. However, there are still have some challenges that this technology and researchers need to face. Improvements on the dry granulation by roller compaction technology would give a great contribution to drug development and goods production.

Paper Citation

in Harvard Style

Zhang Y. (2022). Potentials of the Dry Granulation by Roller Compaction. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 303-307. DOI: 10.5220/0011202700003443

in Bibtex Style

@conference{icbeb22,
author={Yujie Zhang},
title={Potentials of the Dry Granulation by Roller Compaction},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={303-307},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011202700003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - Potentials of the Dry Granulation by Roller Compaction
SN - 978-989-758-595-1
AU - Zhang Y.
PY - 2022
SP - 303
EP - 307
DO - 10.5220/0011202700003443