Research on Drug Therapy of Atherosclerosis

Yu Cao, Xiangrui Chen

2022

Abstract

Atherosclerosis is a chronic inflammatory disease in which atherosclerotic plaque accumulated on the walls of blood vessels and causes narrowing of the arteries. Atherosclerosis usually is asymptomatic in its early stages, and may causes coronary artery disease, stroke, peripheral artery disease and renal failure in severe cases. In general, the symptoms associated with atherosclerosis do not appear until after middle age. Most elderly people who over 65-years-old have atherosclerosis of varying degrees, atherosclerosis is the leading cause of death and disability in developed countries. The atherosclerotic process is very complex, to participate in the cells and tissues, including epithelial cells, smooth muscle, monocytes, macrophage, platelets, lipoprotein, growth hormone, cholesterol, fat and cytokines, etc. Based on these participated mediators, cells and tissues, scientist developed many drugs to relief atherosclerosis. Prevention of atherosclerosis generally includes a healthy diet, exercise, quitting smoking, and maintaining a healthy weight. The drugs include Statins, aspirin, berberine and antiplatelet drugs. In addition to drugs, percutaneous coronary intervention, coronary bypass surgery can also be used to treat atherosclerosis. Recently, scientists focused on the “Bio-Nano” which provide more efficient approach to treat atherosclerosis. The advantages of Nanomedicines are obvious and show its effective function in the clinically experiments, Nanomedicine possess targeted positing systems and enter capillaries and flow freely in the blood circulation system. The Nanomedicine with high future expectation worth showing to more people who suffer atherosclerosis. The review article introduces several distinctive drugs which relief atherosclerosis based on the disease’s pathogenesis, including their functions, detailed mechanism, how to play its function in human body.

Paper Citation

in Harvard Style

Cao Y. and Chen X. (2022). Research on Drug Therapy of Atherosclerosis. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 440-447. DOI: 10.5220/0011214500003443

in Bibtex Style

@conference{icbeb22,
author={Yu Cao and Xiangrui Chen},
title={Research on Drug Therapy of Atherosclerosis},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={440-447},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011214500003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - Research on Drug Therapy of Atherosclerosis
SN - 978-989-758-595-1
AU - Cao Y.
AU - Chen X.
PY - 2022
SP - 440
EP - 447
DO - 10.5220/0011214500003443