Progress of Amlodipine and Enalapril in the Treatment of Hypertension

Yifan Wang

2022

Abstract

BACKGROUND: Hypertension is a long-term chronic disease that has a tremendous negative impact on people’s lives, and its prevalence varies by gender, region, and ethnicity. Calcium channel blockers (CCBs) and angiotensin-converting enzyme inhibitors (ACEIs) are widely used among the first-line antihypertensive agents. CONTENT: The type, epidemiology, pathology, and therapeutic means of hypertension were analysed. The origin of amlodipine, a representative drug of CCBs, and enalapril, a representative drug of ACEIs for the treatment of hypertension was analysed, and their latest progress in pharmacological effects, delivery, combined use, and pharmacoeconomics were summarized and compared. RESULTS: Amlodipine is more suitable for patients who need myocardial protection, and enalapril is more suitable for patients with ventricular hypertrophy. The combination of the two drugs provides better protection for the cardiovascular system. Both drugs are primarily administered orally, but different effects can be achieved by using different dosage forms. Amlodipine is more affordable than enalapril and has a larger market.

Paper Citation

in Harvard Style

Wang Y. (2022). Progress of Amlodipine and Enalapril in the Treatment of Hypertension. In Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH, ISBN 978-989-758-596-8, pages 206-214. DOI: 10.5220/0011244300003438

in Bibtex Style

@conference{ichih22,
author={Yifan Wang},
title={Progress of Amlodipine and Enalapril in the Treatment of Hypertension},
booktitle={Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,},
year={2022},
pages={206-214},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011244300003438},
isbn={978-989-758-596-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,
TI - Progress of Amlodipine and Enalapril in the Treatment of Hypertension
SN - 978-989-758-596-8
AU - Wang Y.
PY - 2022
SP - 206
EP - 214
DO - 10.5220/0011244300003438