Zelda’s Effect on Gene Expression in the Early Development of Drosophila Embryo

Jing Wang

2022

Abstract

Zinc-finger protein Zelda (Zld) is thought to play an essential role in the development of early-stage Drosophila embryos, and this paper takes a step further by confirming the Zld’s effect on Class I & II gene expression, and exploring the synergistic effects of Zld and other transcription factors in gene expression. The primary methods used in this paper are Zelda-binding pattern and JASPAR analysis results. It was found that Zld played a direct and indirect, decisive and non-decisive role in Class I and II gene, respectively. Besides Zld, this paper spotted that the gap proteins derived from gap genes were an key transcription factor in the expression of the pair-rule genes, a subdivision of the Class II genes. There is also evidence shows that sloppy paired 1 might be the enhancer of sloppy paired 2. On the basis of previous studies, this work studied the effects of Zld and other transcription factors on the expression of different types of genes in more detail. Directions for future research were discussed.

Paper Citation

in Harvard Style

Wang J. (2022). Zelda’s Effect on Gene Expression in the Early Development of Drosophila Embryo. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 620-625. DOI: 10.5220/0011249800003443

in Bibtex Style

@conference{icbeb22,
author={Jing Wang},
title={Zelda’s Effect on Gene Expression in the Early Development of Drosophila Embryo},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={620-625},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011249800003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - Zelda’s Effect on Gene Expression in the Early Development of Drosophila Embryo
SN - 978-989-758-595-1
AU - Wang J.
PY - 2022
SP - 620
EP - 625
DO - 10.5220/0011249800003443