The Application of BH-3 Only Mimetics in Tumor Therapy

Chunzi Jiang, Zheng Wang, Yang Yang

2022

Abstract

Tumors are divided into benign and malignant, and the further development of malignant tumors becomes cancer. In recent years, the number of deaths from cancer worldwide increasing rapidly. To better fight cancer, targeted therapy is a more precise method. Among them, BH-3 only protein is a representative protein for targeted therapy. BH-3 only protein is a BCL-2 family protein with only one BH domain and acts as a pro-apoptotic protein to regulate cell apoptosis. Different BH-3 only proteins have different binding options with anti-apoptotic proteins in the BCL-2 family. BH-3 only protein has an excellent performance in inhibiting cancer cells, and the research of BH-3 only mimics constantly updated. This paper will introduce drug research on tumor treatment by studying the effects of targeted BH-3only mimics and expanding drugs’ development for its related family proteins.

Paper Citation

in Harvard Style

Jiang C., Wang Z. and Yang Y. (2022). The Application of BH-3 Only Mimetics in Tumor Therapy. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 791-796. DOI: 10.5220/0011295300003443

in Bibtex Style

@conference{icbeb22,
author={Chunzi Jiang and Zheng Wang and Yang Yang},
title={The Application of BH-3 Only Mimetics in Tumor Therapy},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={791-796},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011295300003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - The Application of BH-3 Only Mimetics in Tumor Therapy
SN - 978-989-758-595-1
AU - Jiang C.
AU - Wang Z.
AU - Yang Y.
PY - 2022
SP - 791
EP - 796
DO - 10.5220/0011295300003443