The Association between FTO, MC4R Variants and Obesity in Different Populations and the Possible Reasons

Hanyu Zhang

2022

Abstract

Obesity is one of the diseases which have bad effects on human health. The finding of obesity genes is a breakthrough in the related area for sure. The association between obesity genes and obesity have certain differences in different population which never be investigated systematically. FTO genes and MC4R genes are common obesity genes. Furthermore, the paper concerning the roles of two genes in different populations and their mechanisms are abundant. However, limits still exist, including the lack of detailed researches on the interaction between two genes. There is less papers on whether other genes’effects cause this phenomenon and how the genes’ interactions cause it. Topic and method: This paper aimes at exploring the differences of FTO and MC4R’s functions in different populations. The author investigates it by looking through papers and analysis and comparing. Results and conclusions: Two hypotheses to the topic are proposed. Firstly, the reasons may be the genes’ differences or the influences from other genes. Secondly, two possible influences from other genes are also mentioned, namely influence directly or indirectly. By analysing the results of existing literature and research, both two possibilities, including one hypothesis that the same genes have certain distinct features in different populations and another possibility that other genes may make effects on it, tend to be reasonable and for the latter circumstance, the effects made by other genes can be directly and indirectly.

Paper Citation

in Harvard Style

Zhang H. (2022). The Association between FTO, MC4R Variants and Obesity in Different Populations and the Possible Reasons. In Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH, ISBN 978-989-758-596-8, pages 437-442. DOI: 10.5220/0011371800003438

in Bibtex Style

@conference{ichih22,
author={Hanyu Zhang},
title={The Association between FTO, MC4R Variants and Obesity in Different Populations and the Possible Reasons},
booktitle={Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,},
year={2022},
pages={437-442},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011371800003438},
isbn={978-989-758-596-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,
TI - The Association between FTO, MC4R Variants and Obesity in Different Populations and the Possible Reasons
SN - 978-989-758-596-8
AU - Zhang H.
PY - 2022
SP - 437
EP - 442
DO - 10.5220/0011371800003438