The Roles of Cytoskeleton in Huntington’s Disease

Jiayin Wu

2022

Abstract

This article indicates partly roles of cytoskeleton in Huntington’s Disease. First, mutant huntingtin may change the vesicle transport due to the fact that phosphorylation of huntingtin as a switch to regulate the anterograde/retrograde transport in neurons. Secondly, dysfunction of cellular morphology regulated by huntingtin, actinin and growth factor may be related in the occurrence of the Huntington’s Disease. Finally, the alterations of Tau in total level, imbalance of isoforms produced by alternative splicing or by post-translational modifications imply that Huntington’s Disease and Alzheimer’s Disease may have similar occurrence mechanism. According to specific description of these, this article hopes to provide new treatments for Huntington’s Disease or new research orientations for diseases with similar characteristic of Huntington’s Disease.

Paper Citation

in Harvard Style

Wu J. (2022). The Roles of Cytoskeleton in Huntington’s Disease. In Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH, ISBN 978-989-758-596-8, pages 572-576. DOI: 10.5220/0011374400003438

in Bibtex Style

@conference{ichih22,
author={Jiayin Wu},
title={The Roles of Cytoskeleton in Huntington’s Disease},
booktitle={Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,},
year={2022},
pages={572-576},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011374400003438},
isbn={978-989-758-596-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,
TI - The Roles of Cytoskeleton in Huntington’s Disease
SN - 978-989-758-596-8
AU - Wu J.
PY - 2022
SP - 572
EP - 576
DO - 10.5220/0011374400003438