The Phylogenetic Analysis of 5 SARS-CoV-2 Proteins’ Sequences in Relation to Time and Geographical Location

Sophia Li, Xiayan Li, Jiahe Gao, Kaiyang Pang, Deyuan Xu

2022

Abstract

After 18 months since the start of the COVID-19 epidemic, the virus continues to plague the world. Learning more about how SARS-CoV-2 proteins mutate and the relation to spatial location is critical in helping us predict the spread of variants. We built an MSA and UPGMA phylogenetic tree for each of the 5 crucial ORF sequences (S, M, E, N, and ORF1ab protein), which were collected by the latest update date for each region, and based on the results, we are not able to conclude that SARS-CoV-2 protein sequences from different countries co-evolved with other SARS-CoV-2 protein variants in proximity. However, some highly mutated regions within those sequences may suggest some evolutionary pattern during this continuing pandemic.

Paper Citation

in Harvard Style

Li S., Li X., Gao J., Pang K. and Xu D. (2022). The Phylogenetic Analysis of 5 SARS-CoV-2 Proteins’ Sequences in Relation to Time and Geographical Location. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 1164-1173. DOI: 10.5220/0011381500003443

in Bibtex Style

@conference{icbeb22,
author={Sophia Li and Xiayan Li and Jiahe Gao and Kaiyang Pang and Deyuan Xu},
title={The Phylogenetic Analysis of 5 SARS-CoV-2 Proteins’ Sequences in Relation to Time and Geographical Location},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={1164-1173},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011381500003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - The Phylogenetic Analysis of 5 SARS-CoV-2 Proteins’ Sequences in Relation to Time and Geographical Location
SN - 978-989-758-595-1
AU - Li S.
AU - Li X.
AU - Gao J.
AU - Pang K.
AU - Xu D.
PY - 2022
SP - 1164
EP - 1173
DO - 10.5220/0011381500003443