Analysis on the Delivery and Formulations of Inhaled Drugs

Jiaying Yan

2022

Abstract

Inhalation or aerosol administration is an area that deserves more research. It is a helpful way to deliver the drugs that are hard to administrated by other routes. It is also promising for delivering biomacromolecule drugs such as insulin and peptide drugs. Aerosol administration is a multidisciplinary topic that includes physics, chemistry, engineering, and physiology. The relationship between the respiratory system and aerosol drugs is essential when studying aerosol administration. In order to get desirable effects, inhalation devices, drug formulations, and the patient are three significant factors to consider. This paper includes three commonly used delivery devices: metered-dose inhalers (MDIs), dry powder inhalers (DPIs), and nebulizers. Research has found that most of the aerosol administration devices have low lung depositions, but nebulizers can reach a relatively higher lung deposition than other devices. All of them have advantages and disadvantages, but each of them possesses distinct characteristics. These three devices have different mechanisms and require different formulations.

Download


Paper Citation


in Harvard Style

Yan J. (2022). Analysis on the Delivery and Formulations of Inhaled Drugs. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 1314-1319. DOI: 10.5220/0011509100003443


in Bibtex Style

@conference{icbeb22,
author={Jiaying Yan},
title={Analysis on the Delivery and Formulations of Inhaled Drugs},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={1314-1319},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011509100003443},
isbn={978-989-758-595-1},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - Analysis on the Delivery and Formulations of Inhaled Drugs
SN - 978-989-758-595-1
AU - Yan J.
PY - 2022
SP - 1314
EP - 1319
DO - 10.5220/0011509100003443