Therapeutic Cancer Vaccines: Mechanism and Clinical Studies

Xiaojun Chen

2022

Abstract

Cancer, a genetic disease involved in abnormal cell growth and division, is a major cause of mortality worldwide for centuries. Among various existing cancer treatments, the development of cancer immunotherapy has been one of the most popular subjects in the field of oncology. Therapeutic cancer vaccine, an exciting innovation in cancer immunotherapy, has effectively improved the clinical outcome in patients by overcoming cancer treating barriers that other cancer treatments such as chemotherapy and radiation cannot achieve, in which tumor cells that are resistant to traditional cancer treatments continue to proliferate uncontrollably and invade other tissues causing disease relapse or metastases, thus resulting in toxicity and collateral destruction to normal tissues and affecting patient’s quality of life. The development of therapeutic cancer vaccines involves numerous factors and requires prudent choice for each step of the design. This review provides an overview of basic components of therapeutic cancer vaccines including target antigens and vaccine platforms and analysis of FDA approved therapeutic cancer vaccines as well as those currently undergoing clinical trials.

Paper Citation

in Harvard Style

Chen X. (2022). Therapeutic Cancer Vaccines: Mechanism and Clinical Studies. In Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB; ISBN 978-989-758-637-8, SciTePress, pages 377-385. DOI: 10.5220/0012021300003633

in Bibtex Style

@conference{icbb22,
author={Xiaojun Chen},
title={Therapeutic Cancer Vaccines: Mechanism and Clinical Studies},
booktitle={Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB},
year={2022},
pages={377-385},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012021300003633},
isbn={978-989-758-637-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biotechnology and Biomedicine - Volume 1: ICBB
TI - Therapeutic Cancer Vaccines: Mechanism and Clinical Studies
SN - 978-989-758-637-8
AU - Chen X.
PY - 2022
SP - 377
EP - 385
DO - 10.5220/0012021300003633
PB - SciTePress