Using Analytical Methods and Simulation to Estimate the Magnitude of Errors in Calculations for Recovery in Washed Red Blood Cells

John Blake, John Blake, Jason Acker, Cherie Mastronardi

2023

Abstract

Canadian Blood Services produces a modified blood product, called washed red blood cells. RBCs are washed to reduce potential transfusion reactions in vulnerable populations. Quality control standards require that at least 75% of the red cells in a unit are retained through the washing process. However, field reports suggest that cell recovery values greater than 100% can be observed. The purpose of this study is to analyse the propagation of error in the washing process and to determine if values exceeding 100% are reasonable, given the accuracy of the equipment in use. Employing analytical techniques and simulation methods, it was found that recovery rates in excess of 100% are possible, but that any calculated value exceeding 102% is unlikely and should be investigate for process errors.

Paper Citation

in Harvard Style

Blake J., Acker J. and Mastronardi C. (2023). Using Analytical Methods and Simulation to Estimate the Magnitude of Errors in Calculations for Recovery in Washed Red Blood Cells. In Proceedings of the 13th International Conference on Simulation and Modeling Methodologies, Technologies and Applications - Volume 1: SIMULTECH; ISBN 978-989-758-668-2, SciTePress, pages 340-345. DOI: 10.5220/0012097800003546

in Bibtex Style

@conference{simultech23,
author={John Blake and Jason Acker and Cherie Mastronardi},
title={Using Analytical Methods and Simulation to Estimate the Magnitude of Errors in Calculations for Recovery in Washed Red Blood Cells},
booktitle={Proceedings of the 13th International Conference on Simulation and Modeling Methodologies, Technologies and Applications - Volume 1: SIMULTECH},
year={2023},
pages={340-345},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012097800003546},
isbn={978-989-758-668-2},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Conference on Simulation and Modeling Methodologies, Technologies and Applications - Volume 1: SIMULTECH
TI - Using Analytical Methods and Simulation to Estimate the Magnitude of Errors in Calculations for Recovery in Washed Red Blood Cells
SN - 978-989-758-668-2
AU - Blake J.
AU - Acker J.
AU - Mastronardi C.
PY - 2023
SP - 340
EP - 345
DO - 10.5220/0012097800003546
PB - SciTePress