Open Complex Systems Approach Utilizing ICT to Address Immune-Related Diseases in Aging Society

Tatsuya Kawaoka, Tatsuya Kawaoka, Tatsuya Kawaoka, Ryota Sakayama, Kousaku Ohta, Masatoshi Funabashi, Masatoshi Funabashi, Masatoshi Funabashi

2025

Abstract

Immune-related diseases, such as allergies, asthma, and dementia, are rising globally, driven by aging populations and declining ecosystem functions. Traditional elementary reductionist approaches struggle to address the complex pathologies underlying these diseases. This study explores a personalized, ecosystem-based approach to mitigating immune dysregulation using a supportive ICT platform. We developed a data-driven analytical system that identifies individual metabolic challenges through the measurement of multiple biomarkers and clinical interviews, categorizing them into metabolic traits such as inflammatory, stress-related, and glucotoxic factors. Based on these assessments, professional staff provided tailored lifestyle advice and rehabilitation interventions, including light exercises in high biodiversity environments. The results showed significant improvements in cognitive and immune functions: Participants exhibited a 3.5-point average increase in MoCA scores over three months, including functional recovery from Parkinson’s disease and CVA. Furthermore, the study identified phytochemical-rich foods, such as coarse green tea, as significant factors enhancing rehabilitation outcomes. These findings emphasize the importance of synergy between ecological environments and public health initiatives, aligning with the Planetary Health framework. By integrating multivariate analysis, personalized interventions, and ecosystem considerations through an integrative ICT platform, this approach offers a scalable solution to addressing immune-related diseases and reducing social security costs, with implications for global healthcare and environmental policies.

Paper Citation

in Harvard Style

Kawaoka T., Sakayama R., Ohta K. and Funabashi M. (2025). Open Complex Systems Approach Utilizing ICT to Address Immune-Related Diseases in Aging Society. In Proceedings of the 11th International Conference on Information and Communication Technologies for Ageing Well and e-Health - Volume 1: ICT4AWE; ISBN 978-989-758-743-6, SciTePress, pages 302-311. DOI: 10.5220/0013359900003938

in Bibtex Style

@conference{ict4awe25,
author={Tatsuya Kawaoka and Ryota Sakayama and Kousaku Ohta and Masatoshi Funabashi},
title={Open Complex Systems Approach Utilizing ICT to Address Immune-Related Diseases in Aging Society},
booktitle={Proceedings of the 11th International Conference on Information and Communication Technologies for Ageing Well and e-Health - Volume 1: ICT4AWE},
year={2025},
pages={302-311},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0013359900003938},
isbn={978-989-758-743-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 11th International Conference on Information and Communication Technologies for Ageing Well and e-Health - Volume 1: ICT4AWE
TI - Open Complex Systems Approach Utilizing ICT to Address Immune-Related Diseases in Aging Society
SN - 978-989-758-743-6
AU - Kawaoka T.
AU - Sakayama R.
AU - Ohta K.
AU - Funabashi M.
PY - 2025
SP - 302
EP - 311
DO - 10.5220/0013359900003938
PB - SciTePress