Mineralization Kinetics of Hydroxyapatite/Chitosan Composite in a Simulated Body Fluid

Liping Zeng, Deliang He, Xianglong Liu

Abstract

This study offers provide real time and multidimensional information to the monitoring of biomaterial mineralization process. In order to investigate on real time the mineralization process of hydroxyapatite/chitosan (HAP/CS) composite in a simulated body fluid, the piezoelectric quartz crystal impedance (PQCI) technique and electrochemical impedance spectroscopy (EIS) was used to reveal the mineralization kinetics processes for bone tissue engineering. Various characterization techniques were analyzed by Fourier transformed infrared (FT-IR), X-ray diffraction (XRD) and scanning electrode microscopy (SEM). A decrease of the frequency (f) and an increase of the charge transfer resistance (Rct) at the gold electrode/solution interface were observed due to the mineralization of HAP/CS composite. According to the data of the frequency and static capacity (Cs), the correlative kinetic equations and parameters were obtained by nonlinear regression. The results show that the mineralization process of HAP/CS is divided into two stages: the nucleation stage and the crystal growth stage, which paves the way for applications of bone tissue engineering.

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Paper Citation


in Harvard Style

Zeng L., He D. and Liu X. (2018). Mineralization Kinetics of Hydroxyapatite/Chitosan Composite in a Simulated Body Fluid.In Proceedings of the 2nd International Conference on Intelligent Manufacturing and Materials - Volume 1: ICIMM, ISBN 978-989-758-345-2, pages 427-433. DOI: 10.5220/0007533104270433


in Bibtex Style

@conference{icimm18,
author={Liping Zeng and Deliang He and Xianglong Liu},
title={Mineralization Kinetics of Hydroxyapatite/Chitosan Composite in a Simulated Body Fluid},
booktitle={Proceedings of the 2nd International Conference on Intelligent Manufacturing and Materials - Volume 1: ICIMM,},
year={2018},
pages={427-433},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007533104270433},
isbn={978-989-758-345-2},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Intelligent Manufacturing and Materials - Volume 1: ICIMM,
TI - Mineralization Kinetics of Hydroxyapatite/Chitosan Composite in a Simulated Body Fluid
SN - 978-989-758-345-2
AU - Zeng L.
AU - He D.
AU - Liu X.
PY - 2018
SP - 427
EP - 433
DO - 10.5220/0007533104270433