FAST AND ROBUST MID-SAGITTAL PLANE LOCATION IN 3D MR IMAGES OF THE BRAIN

Felipe P. G. Bergo, Guilherme C. S. Ruppert, Luiz F. Pinto, Alexandre X. Falca˜o

2008

Abstract

Extraction of the mid-sagittal plane (MSP) is an important step for brain image registration and asymmetry analysis. We present a fast MSP extraction method for 3D MR images, which is based on automatic segmentation of the brain and on heuristic maximization of cerebro-spinal fluid within the MSP. The method is shown to be robust to severe anatomical asymmetries between the hemispheres, caused by surgical procedures and lesions. The experiments used 64 MR images (36 pathological, 20 healthy, 8 synthetic) and the method found an acceptable approximation of the MSP in all images with a mean time of 60.0 seconds per image.

References

  1. Ardekani, B., Kershaw, J., Braun, M., and Kanno, I. (1997). Automatic detection of the mid-sagittal plane in 3- D brain images. IEEE Trans. on Medical Imaging, 16(6):947-952.
  2. Barrick, T. R., Mackay, C. E., Prima, S., Maes, F., Vandermeulen, D., Crow, T. J., and Roberts, N. (2005). Automatic analysis of cerebral asymmetry: na exploratory study of the relationship between brain torque and planum temporale asymmetry. NeuroImage, 24(3):678-691.
  3. Bergo, F. P. G., Falca˜o, A. X., Miranda, P. A. V., and Rocha, L. M. (2007). Automatic image segmentation by tree pruning. Technical Report IC-07-23, Institute of Computing, University of Campinas.
  4. Brummer, M. E. (1991). Hough transform detection of the longitudinal fissure in tomographic head images. IEEE Trans. on Medical Imaging, 10(1):66-73.
  5. Collins, D. L., Zijdenbos, A. P., Kollokian, V., Sled, J. G., Kabani, N. J., Holmes, C. J., and Evans, A. C. (1998). Design and construction of a realistic digital brain phantom. IEEE Trans. on Medical Imaging, 17(3):463-468.
  6. Crow, T. J. (1993). Schizophrenia as an anomaly of cerebral asymmetry. In Maurer, K., editor, Imaging of the Brain in Psychiatry and Related Fields, pages 3-17. Springer.
  7. Csernansky, J. G., Joshi, S., Wang, L., Haller, J. W., Gado, M., Miller, J. P., Grenander, U., and Miller, M. I. (1998). Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Proceedings of the National Academy os Sciences of the United States of America, 95(19):11406-11411.
  8. Csernansky, J. G., Wang, L., Joshi, S., Miller, J. P., Gado, M., Kido, D., McKeel, D., Morris, J. C., and Miller, M. I. (2000). Early DAT is distinguished from aging by high-dimensional mapping of the hippocampus. Neurology, 55:1636-1643.
  9. Davidson, R. J. and Hugdahl, K. (1996). Brain Asymmetry. MIT Press/Bradford Books.
  10. Falca˜o, A. X., Bergo, F. P. G., and Miranda, P. A. V. (2004a). Image segmentation by tree pruning. In Proc. of the XVII Brazillian Symposium on Computer Graphics and Image Processing, pages 65-71. IEEE.
  11. Falca˜o, A. X., Stolfi, J., and Lotufo, R. A. (2004b). The image foresting transform: Theory, algorithms and applications. IEEE Trans. on Pattern Analysis and Machine Intelligence, 26(1):19-29.
  12. Geschwind, N. and Levitsky, W. (1968). Human brain: Left-right asymmetries in temporale speech region. Science, 161(3837):186-187.
  13. Guillemaud, R., Marais, P., Zisserman, A., McDonald, B., Crow, T. J., and Brady, M. (1996). A three dimensional mid sagittal plane for brain asymmetry measurement. Schizophrenia Research, 18(2-3):183-184.
  14. Hogan, R. E., Mark, K. E., Choudhuri, I., Wang, L., Joshi, S., Miller, M. I., and Bucholz, R. D. (2000). Magnetic resonance imaging deformation-based segmentation of the hippocampus in patients with mesial temporal sclerosis and temporal lobe epilepsy. J. Digital Imaging, 13(2):217-218.
  15. Hu, Q. and Nowinski, W. L. (2003). A rapid algorithm for robust and automatic extraction of the midsagittal plane of the human cerebrum from neuroimages based on local symmetry and outlier removal. NeuroImage, 20(4):2153-2165.
  16. Junck, L., Moen, J. G., Hutchins, G. D., Brown, M. B., and Kuhl, D. E. (1990). Correlation methods for the centering, rotation, and alignment of functional brain images. The Journal of Nuclear Medicine, 31(7):1220- 1226.
  17. Kapouleas, I., Alavi, A., Alves, W. M., Gur, R. E., and Weiss, D. W. (1991). Registration of three dimensional MR and PET images of the human brain without markers. Radiology, 181(3):731-739.
  18. Liu, Y., Collins, R. T., and Rothfus, W. E. (2001). Robust midsagittal plane extraction from normal and pathological 3D neuroradiology images. IEEE Trans. on Medical Imaging, 20(3):175-192.
  19. Liu, Y., Teverovskiy, L. A., Lopez, O. L., Aizenstein, H., Meltzer, C. C., and Becker, J. T. (2007). Discovery of biomarkers for alzheimer's disease prediction from structural MR images. In 2007 IEEE Intl. Symp. on Biomedical Imaging, pages 1344-1347. IEEE.
  20. Mackay, C. E., Barrick, T. R., Roberts, N., DeLisi, L. E., Maes, F., Vandermeulen, D., and Crow, T. J. (2003). Application of a new image analysis technique to study brain asymmetry in schizophrenia. Psychiatry Research, 124(1):25-35.
  21. Minoshima, S., Berger, K. L., Lee, K. S., and Mintun, M. A. (1992). An automated method for rotational correction and centering of three-dimensional functional brain images. The Journal of Nuclear Medicine, 33(8):1579-1585.
  22. Miranda, P. A. V., Bergo, F. P. G., Rocha, L. M., and Falca˜o, A. X. (2006). Tree-pruning: A new algorithm and its comparative analysis with the watershed transform for automatic image segmentation. In Proc. of the XIX Brazillian Symposium on Computer Graphics and Image Processing, pages 37-44. IEEE.
  23. Otsu, N. (1979). A threshold selection method from gray level histograms. IEEE Trans. Systems, Man and Cybernetics, 9:62-66.
  24. Prima, S., Ourselin, S., and Ayache, N. (2002). Computation of the mid-sagittal plane in 3D brain images. IEEE Trans. on Medical Imaging, 21(2):122-138.
  25. Smith, S. M. and Jenkinson, M. (1999). Accurate robust symmetry estimation. In Proc MICCAI 7899, pages 308-317, London, UK. Springer-Verlag.
  26. Styner, M. and Gerig, G. (2000). Hybrid boundary-medial shape description for biologically variable shapes. In Proc. of IEEE Workshop on Mathematical Methods in Biomedical Imaging Analysis (MMBIA), pages 235- 242. IEEE.
  27. Sun, C. and Sherrah, J. (1997). 3D symmetry detection using the extended Gaussian image. IEEE Trans. on Pattern Analysis and Machine Intelligence, 19(2):164- 168.
  28. Talairach, J. and Tournoux, P. (1988). Co-Planar Steriotaxic Atlas of the Human Brain. Thieme Medical Publishers.
  29. Teverovskiy, L. and Liu, Y. (2006). Truly 3D midsagittal plane extraction for robust neuroimage registration. In Proc. of 3rd IEEE Intl. Symp. on Biomedical Imaging, pages 860-863. IEEE.
  30. Tuzikov, A. V., Colliot, O., and Bloch, I. (2003). Evaluation of the symmetry plane in 3D MR brain images. Pattern Recognition Letters, 24(14):2219-2233.
  31. Volkau, I., Prakash, K. N. B., Ananthasubramaniam, A., Aziz, A., and Nowinski, W. L. (2006). Extraction of the midsagittal plane from morphological neuroimages using the Kullback-Leibler's measure. Medical Image Analysis, 10(6):863-874.
  32. Wang, L., Joshi, S. C., Miller, M. I., and Csernansky, J. G. (2001). Statistical analysis of hippocampal asymmetry in schizophrenia. NeuroImage, 14(3):531-545.
  33. Wu, W.-C., Huang, C.-C., Chung, H.-W., Liou, M., Hsueh, C.-J., Lee, C.-S., Wu, M.-L., , and Chen, C.-Y. (2005). Hippocampal alterations in children with temporal lobe epilepsy with or without a history of febrile convulsions: Evaluations with MR volumetry and proton MR spectroscopy. AJNR Am J Neuroradiol, 26(5):1270-1275.
Download


Paper Citation


in Harvard Style

P. G. Bergo F., C. S. Ruppert G., F. Pinto L. and X. Falca˜o A. (2008). FAST AND ROBUST MID-SAGITTAL PLANE LOCATION IN 3D MR IMAGES OF THE BRAIN . In Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2008) ISBN 978-989-8111-18-0, pages 92-99. DOI: 10.5220/0001066100920099


in Bibtex Style

@conference{biosignals08,
author={Felipe P. G. Bergo and Guilherme C. S. Ruppert and Luiz F. Pinto and Alexandre X. Falca˜o},
title={FAST AND ROBUST MID-SAGITTAL PLANE LOCATION IN 3D MR IMAGES OF THE BRAIN},
booktitle={Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2008)},
year={2008},
pages={92-99},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001066100920099},
isbn={978-989-8111-18-0},
}


in EndNote Style

TY - CONF
JO - Proceedings of the First International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2008)
TI - FAST AND ROBUST MID-SAGITTAL PLANE LOCATION IN 3D MR IMAGES OF THE BRAIN
SN - 978-989-8111-18-0
AU - P. G. Bergo F.
AU - C. S. Ruppert G.
AU - F. Pinto L.
AU - X. Falca˜o A.
PY - 2008
SP - 92
EP - 99
DO - 10.5220/0001066100920099