3-((2':2",5":2'''-TERTHIOPHENE)-3"-YL) ACRYLIC ACID AS ORGANIC FIELD EFFECT TRANSISTOR FOR DNA SENSING

K. C. Aw, N. Tjitra Salim, H. Peng, J. Travas-Sedjic, W. Gao

2010

Abstract

The aim of this paper is to demonstrate the use of organic field effect transistor (OFET) as a DNA sensor. We have synthesized a functionalised terthiophene monomer 3-((2":2″,5″:2'''-terthiophene)-3″-yl) acrylic acid (TAA) and has been successfully electrodeposited as an active layer of an OFET. The polymer was oxidised in order to increase its conductivity. A mobility of 0.25 cm2/V.s was achieved with an oxidising potential of 0.9 V. A preliminary DNA sensing test was performed on the OFET with poly TAA as active layer and a shift in threshold voltage was observed after DNA immobilization and hybridization, showing its potential as DNA sensor.

References

  1. Chen, X., Inganas, O., 1996. Three-Step Redox in Polythiophenes:  Evidence from Electrochemistry at an Ultramicroelectrode, The Journal of Physical Chemistry 100 (37), 15202-15206.
  2. Peng,H., Zhang, L., Spires, J. et al., 2007. Synthesis of a functionalized polythiophene as an active substrate for a label-free electrochemical genosensor, Polymer 48 (12), 3413-3419.
  3. Roncali, J., 1992. Conjugated poly(thiophenes): Synthesis, functionalization and applications, Chemical Reviews 92 (12), 711.
  4. Tjitra Salim, N., Aw K.C., Peng, H. et. al., 2008. New 3- ((2':2'',5'':2'''-terthiophene)-3''-yl) acrylic acid as active layer for organic field-effect transistor, Materials Chemistry and Physics, 111 (1), 1-4.
  5. Zhang, L., Peng, H., Kilmartin, P.A. et al., 2007. Polymeric Acid Doped Polyaniline Nanotubes for Oligonucleotide Sensors, Electroanalysis 19 (7-8), 870-875.
  6. Zhang Q., Subramanian, V., 2007. DNA hybridization detection with organic thin film transistors: Toward fast and disposable DNA microarray chips, Biosensors and Bioelectronics 22 (12), 3182-3187.
Download


Paper Citation


in Harvard Style

Aw K., Tjitra Salim N., Peng H., Travas-Sedjic J. and Gao W. (2010). 3-((2':2",5":2'''-TERTHIOPHENE)-3"-YL) ACRYLIC ACID AS ORGANIC FIELD EFFECT TRANSISTOR FOR DNA SENSING . In Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010) ISBN 978-989-674-017-7, pages 159-162. DOI: 10.5220/0002692601590162


in Bibtex Style

@conference{biodevices10,
author={K. C. Aw and N. Tjitra Salim and H. Peng and J. Travas-Sedjic and W. Gao},
title={3-((2':2",5":2'''-TERTHIOPHENE)-3"-YL) ACRYLIC ACID AS ORGANIC FIELD EFFECT TRANSISTOR FOR DNA SENSING},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)},
year={2010},
pages={159-162},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002692601590162},
isbn={978-989-674-017-7},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2010)
TI - 3-((2':2",5":2'''-TERTHIOPHENE)-3"-YL) ACRYLIC ACID AS ORGANIC FIELD EFFECT TRANSISTOR FOR DNA SENSING
SN - 978-989-674-017-7
AU - Aw K.
AU - Tjitra Salim N.
AU - Peng H.
AU - Travas-Sedjic J.
AU - Gao W.
PY - 2010
SP - 159
EP - 162
DO - 10.5220/0002692601590162