BAYESIAN-BASED EARLY DETECTION OF COGNITIVE IMPAIRMENT IN ELDERLY USING fNIRS SIGNALS DURING COGNITIVE TESTS

Shohei Kato, Hidetoshi Endo, Yuta Suzuki

2012

Abstract

This paper presents a new trial approach to early detection of dementia in the elderly with the use of functional brain imaging during cognitive tests. We have developed a non-invasive screening system of the elderly with cognitive impairment. In addition of our previous research of speech-prosody based data-mining approach, we had started the measurement of functional brain imaging for patient having a cognitive test by using functional near-infrared spectroscopy (fNIRS). We had collected 42 CHs fNIRS signals on frontal and right and left temporal areas from 50 elderly participants (18 males and 32 females between ages of 64 to 92) during cognitive tests in a specialized medical institute. We propose a Bayesian classifier, which can discriminate among elderly individuals with three clinical groups: normal cognitive abilities (NL), patients with mild cognitive impairment (MCI), and Alzheimer’s disease (AD). The Bayesian classifier has two phases on the assumption of screening process, that firstly checks whether a suspicion of the cognitive impairment (CI) or not (NL) from given fNIRS signals; if any, and then secondly judges the degree of the impairment: MCI or AD. This paper also reports the examination of the detection performance by cross-validation, and discusses the effectiveness of this study for early detection of cognitive impairment in elderly subjects. Consequently, empirical results that both the accuracy rate of AD and the predictive value of NL are equal to or more than 90%. This suggests that proposed approach is adequate practical to screen the elderly with cognitive impairment.

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Paper Citation


in Harvard Style

Kato S., Endo H. and Suzuki Y. (2012). BAYESIAN-BASED EARLY DETECTION OF COGNITIVE IMPAIRMENT IN ELDERLY USING fNIRS SIGNALS DURING COGNITIVE TESTS . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012) ISBN 978-989-8425-89-8, pages 118-124. DOI: 10.5220/0003790001180124


in Bibtex Style

@conference{biosignals12,
author={Shohei Kato and Hidetoshi Endo and Yuta Suzuki},
title={BAYESIAN-BASED EARLY DETECTION OF COGNITIVE IMPAIRMENT IN ELDERLY USING fNIRS SIGNALS DURING COGNITIVE TESTS},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)},
year={2012},
pages={118-124},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003790001180124},
isbn={978-989-8425-89-8},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2012)
TI - BAYESIAN-BASED EARLY DETECTION OF COGNITIVE IMPAIRMENT IN ELDERLY USING fNIRS SIGNALS DURING COGNITIVE TESTS
SN - 978-989-8425-89-8
AU - Kato S.
AU - Endo H.
AU - Suzuki Y.
PY - 2012
SP - 118
EP - 124
DO - 10.5220/0003790001180124