CyberBrain - A Preliminary Experience on Non Human Primate
M. Piangerelli, A. Paris, P. Romanelli
2014
Abstract
The study of abnormal electrical activity of the brain, such as epilepsy, is attracting more and more interest for its wide impact on the population. Intracranial EEG recording (electrocorticogaphy; EcoG) and direct cortical stimulation (DCS) are, nowadays, the most accurate and reliable techniques to map cortical function and to identify the boundaries of an epileptic focus. In this work we present the preliminary testing of intra-operative ECoG and DCS performed in a non-human primate using a new custom-made fully-implantable wireless 16-channels device (Patent Number: WO2012143850), called ECOGW-16E. This fully-integrated device, housed in a compact hermetically sealed Polyetheretherketone (PEEK) enclosure, exploits the newly available Medical Implant Communication Service band (MICS: 402-405 MHz). ECOGW-16E is wirelessly rechargeable using a special designed cage for recharge, developed in accordance with guidelines for accommodation of animals by Council of Europe.
References
- Behrens, E., Schramm, J., Zentner, J., and K önig, R. (1997). Surgical and neurological complications in a series of 708 epilepsy surgery procedures. Neurosurgery, 41(1):1-10.
- Borchers, S., Himmelbach M, Logothetis, N., and Karnath, H. (2012). Direct electrical stimulation of human cortex: the gold standard for mapping brain functions? Nature Reviews Neuroscience, 13:63-70.
- Cristiani, P., Marchetti, S., Paris, A., Romanelli, P., and Sebastiano, F. (2012). Implantable device for acquisition and monitoring of brain bioelectric signals and for intracranial stimulation. WO Patent App. PCT/IB2012/051,909.
- Crone, N. E., Miglioretti, D. L., Gordon, B., and Lesser, R. P. (1998). Functional mapping of human sensorimotor cortex with electrocorticographic spectral analysis. ii. event-related synchronization in the gamma band. Brain, 121(12):2301-2315.
- Johnson, L. A., Wander, J. D., Sarma, D., Su, D. K., Fetz, E. E., and Ojemann, J. G. (2013). Direct electrical stimulation of the somatosensory cortex in humans using electrocorticography electrodes: a qualitative and quantitative report. Journal of Neural Engineering, 10(3):036021.
- Kellis, S., Greger, B., Hanrahan, S., House, P., and Brown, R. (2011). Platinum microwire for subdural electrocorticography over human neocortex: Millimeterscale spatiotemporal dynamics. In Engineering in Medicine and Biology Society,EMBC, 2011 Annual International Conference of the IEEE, pages 4761- 4765.
- Moro, E., Esselink, R. J., Xie, J., Hommel, M., Benabid, A. L., and Pollak, P. (2002). The impact on parkinsons disease of electrical parameter settings in stn stimulation. Neurology, 59(5):706-713.
- Rivard, C.-H., Rhalmi, S., and Coillard, C. (2002). In vivo biocompatibility testing of peek polymer for a spinal implant system: A study in rabbits. Journal of Biomedical Materials Research, 62(4):488-498.
- Spena, G., Nava, A., Cassini, F., Pepoli, A., Bruno, M., DAgata, F., Cauda, F., Sacco, K., Duca, S., Barletta, L., et al. (2010). Preoperative and intraoperative brain mapping for the resection of eloquent-area tumors. a prospective analysis of methodology, correlation, and usefulness based on clinical outcomes. Acta neurochirurgica, 152(11):1835-1846.
- Warren, R. and Durand, D. M. (1998). Effects of applied currents on spontaneous epileptiform activity induced by low calcium in the rat hippocampus. Brain Research, 806(2):186 - 195.
Paper Citation
in Harvard Style
Piangerelli M., Paris A. and Romanelli P. (2014). CyberBrain - A Preliminary Experience on Non Human Primate . In Proceedings of the 2nd International Congress on Neurotechnology, Electronics and Informatics - Volume 1: NEUROTECHNIX, ISBN 978-989-758-056-7, pages 94-98. DOI: 10.5220/0005089700940098
in Bibtex Style
@conference{neurotechnix14,
author={M. Piangerelli and A. Paris and P. Romanelli},
title={CyberBrain - A Preliminary Experience on Non Human Primate},
booktitle={Proceedings of the 2nd International Congress on Neurotechnology, Electronics and Informatics - Volume 1: NEUROTECHNIX,},
year={2014},
pages={94-98},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005089700940098},
isbn={978-989-758-056-7},
}
in EndNote Style
TY - CONF
JO - Proceedings of the 2nd International Congress on Neurotechnology, Electronics and Informatics - Volume 1: NEUROTECHNIX,
TI - CyberBrain - A Preliminary Experience on Non Human Primate
SN - 978-989-758-056-7
AU - Piangerelli M.
AU - Paris A.
AU - Romanelli P.
PY - 2014
SP - 94
EP - 98
DO - 10.5220/0005089700940098