Neuronal Patterns in the Cavity Wall of Lesions during Gait Cycle in a Rat Model of Brain Lesion Cavities
Ioana Nica, Marjolijn Deprez, Frederik Ceyssens, Kris van Kuyck, Robert Puers, Bart Nuttin, Jean-Marie Aerts
2015
Abstract
Oscillatory neural activity was reported to have various physiological roles in information processing of brain functions. It is now established that extracellular activity in the motor cortex encodes aspects of movement, involving planning and motor control. Oscillatory patterns have also been hypothesized to play a role in brain recovery and functional remapping. In this study, we measured neural activity from within the cavity wall of a motor cortex lesion, in a rat model, while the animals performed a skilled walking task. We aim at providing a possible framework of analysis, focused on revealing oscillatory patterns in the cavity wall and their correlation with motor deficits, by using a combination of spectral features, involving power spectra and coherence estimates in the beta and gamma frequency bands.
References
- Aoki, F., et al., 2001. Changes in power and coherence of brain activity in human sensorimotor cortex during performance of visuomotor tasks.
- Alegre, M., et al., 2002. Beta electroencephalograph changes during passive movements: sensory afferences contribute to beta event-related desynchronization in humans. Neurosci. Lett., 331, 29.
- Donogue J.P. et al., 1998.Neural discharge and local field potential oscillations in primate motor cortex during voluntary movements, J. Neurophysiol., 79, 159.
- Goldberg JA, Rokni U, Boraud T, Vaadia E, Bergman H (2004) Spike synchronization in the cortex-basal ganglia networks of parkinsonian primates reflects global dynamics of the local field potentials. J Neurosci 24: 6003-6010.
- Hamada, Y., Miyashita, E., and Tanaka, H., 1999. Gamma-band oscillations in the 'barel cortex' preced rat's exploratory whisking. Neuroscience, 88, 667.
- Jasper, H., and Penfield, W., 1949. Electrocorticograms in man: effect of voluntary movement upon the electrical activity of the precentral gyrus, Arch. Psychiatrie und Z. Neurologie, 182, 163.
- Metz, G.A., Whishaw, I.Q., 2009. The ladder rung walking task: a scoring system and its practical application. J. Vis. Exp. (28), e1204, doi:10.3791/1204.
- Murphy, T. H., and Corbett, D., 2009. Plasticity during stroke recovery: from synapse to behaviour. Nat. Rev. Neurosci. 10, 861-872.
- Neuper, C., and Pfurtscheller, G., 2001. Evidence for distinct beta resonance frequencies in human EEG related to specific sensorimotor cortical areas. Clin. Neurophysiol., 112, 2084.
- Raz, A., Feingold A., Zelanskaya V, Vaadia E, Bergman H (1996) Neuronal synchronization of tonically active neurons in the striatum of normal and parkinsonian primates. J Neurophysiol 76: 2083-2088.
- Raz A, Vaadia E, Bergman H (2000) Firing patterns and correlations of spontaneous discharge of pallidal neurons in the normal and the tremulous 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine vervet model of parkinsonism. J Neurosci 20: 8559-8571.
- Ruskin DN, Bergstrom DA, Kaneoke Y, Patel BN, Twery MJ, Walters JR (1999a) Multisecond oscillations in firing rate in the basal ganglia: robust modulation by dopamine receptor activation and anesthesia. J Neurophysiol 81:2046-2055.
- Toma, K., et al., 2000. Desynchronization and synchronization of central 20-Hz rhythms associated with voluntary muscle relaxation: a magnetoencephalographic study. Exp. Brain Res., 134, 417.
Paper Citation
in Harvard Style
Nica I., Deprez M., Ceyssens F., van Kuyck K., Puers R., Nuttin B. and Aerts J. (2015). Neuronal Patterns in the Cavity Wall of Lesions during Gait Cycle in a Rat Model of Brain Lesion Cavities . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015) ISBN 978-989-758-069-7, pages 289-294. DOI: 10.5220/0005275802890294
in Bibtex Style
@conference{biosignals15,
author={Ioana Nica and Marjolijn Deprez and Frederik Ceyssens and Kris van Kuyck and Robert Puers and Bart Nuttin and Jean-Marie Aerts},
title={Neuronal Patterns in the Cavity Wall of Lesions during Gait Cycle in a Rat Model of Brain Lesion Cavities},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015)},
year={2015},
pages={289-294},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005275802890294},
isbn={978-989-758-069-7},
}
in EndNote Style
TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2015)
TI - Neuronal Patterns in the Cavity Wall of Lesions during Gait Cycle in a Rat Model of Brain Lesion Cavities
SN - 978-989-758-069-7
AU - Nica I.
AU - Deprez M.
AU - Ceyssens F.
AU - van Kuyck K.
AU - Puers R.
AU - Nuttin B.
AU - Aerts J.
PY - 2015
SP - 289
EP - 294
DO - 10.5220/0005275802890294