Evaluation of the Degree of Malignancy of Lung Nodules in Computed Tomography Images
L. Gonçalves, J. Novo, A. Cunha, A. Campilho
2017
Abstract
In lung cancer diagnosis, the design of robust Computer Aided Diagnosis (CAD) systems needs to include an adequate differentiation of benign from malignant nodules. This paper presents a CAD system for the classification of lung nodules in chest Computed Tomography (CT) scans as the way to diagnose lung cancer. The proposed method measures a set of 295 heterogeneous characteristics, including morphology, intensity or texture features, that were used as input of different KNN and SVM classifiers. The system was modeled and trained using a groundtruth provided by specialists taken from a public lung image dataset, the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI). This image dataset includes chest CT scans with lung nodule location together with information about the degree of malignancy, among other properties, provided by multiple expert clinicians. In particular, the computed degree of malignancy try to follow the manual labeling by the different radiologists. Promising results were obtained with a first order SVM with an exponential kernel achieving an area under the receiver operating characteristic curve of 96.2 ± 0.5% when compared with the groundtruth provided in the public CT lung image dataset.
References
- Akram, S., Javed, M., Hussain, A., Riaz, F., and Akram, M. (2015). Intensity-based statistical features for classification of lungs ct scan nodules using artificial intelligence techniques. Journal of Experimental and Theoretical Artificial Intelligence, 27:737-751.
- Breadsmoore, C. J. and Screaton, N. J. (2003). Classification, staging and prognosis of lung cancer. European Journal of Radiology, 45:8-17.
- Gonc¸alves, L., Novo, J., and Campilho, A. (2016). Hessian based approaches for 3D lung nodule segmentation. Expert Systems with Applications, 61:1-15.
- Hall, M. A. (1999). Correlation-based feature selection for machine learning. PhD thesis, The University of Waikato.
- Kaya, A. and Can, A. (2015). A weighted rule based method for predicting malignancy of pulmonary nodules by nodule characteristics. Journal of Biomedical Informatics, 56:69-79.
- Liu, X., Ma, L., Song, L., Zhao, Y., Zhao, X., and Zhou, C. (2015). Recognizing common ct imaging signs of lung diseases through a new feature selection method based on fisher criterion and genetic optimization. IEEE Journal of Biomedical and Health Informatics, 19:635-647.
- Novo, J., Gonc¸alves, L., Mendonc¸a, A., and Campilho, A. (2015). 3D lung nodule candidates detection in multiple scales. IAPR International Conference on Machine Vision Applications, MVA 2015, pages 5-8.
- Novo, J., Rouco, J., Mendonc¸a, A., and Campilho, A. (2014). Reliable lung segmentation methodology by including juxtapleural nodules. International Conference on Image Analysis and Recognition, ICIAR 2014. Lecture Notes in Computer Science: Image Analysis and Recognition, 8815:227-235.
- Siegel, R. L., , Miller, K. D., and Jemal, A. (2016). Cancer statistics, 2016. CA: A Cancer Journal for Clinicians, 66:7-30.
- van Ginneken, B. (2008). Computer-aided diagnosis in thoracic computed tomography. Imaging Decisions MRI, 12:11-22.
- Wu, H., Sun, T., Wang, J., Li, X., Wang, W., Huo, D., Lv, P., He, W., Wang, K., and Guo, X. (2013a). Combination of radiological and gray level co-occurrence matrix textural features used to distinguish solitary pulmonary nodules by computed tomography. Society for Imaging Informatics in Medicine, 26:797-802.
- Wu, H., Sun, T., Wang, J., Li, X., Wang, W., Huo, D., Lv, P., He, W., Wang, K., and Guo, X. (2013b). Combination of radiological and gray level co-occurrence matrix textural features used to distinguish solitary pulmonary nodules by computed tomography. Society for Imaging Informatics in Medicine, 26:797-802.
Paper Citation
in Harvard Style
Gonçalves L., Novo J., Cunha A. and Campilho A. (2017). Evaluation of the Degree of Malignancy of Lung Nodules in Computed Tomography Images . In Proceedings of the 12th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications - Volume 6: VISAPP, (VISIGRAPP 2017) ISBN 978-989-758-227-1, pages 74-80. DOI: 10.5220/0006116200740080
in Bibtex Style
@conference{visapp17,
author={L. Gonçalves and J. Novo and A. Cunha and A. Campilho},
title={Evaluation of the Degree of Malignancy of Lung Nodules in Computed Tomography Images},
booktitle={Proceedings of the 12th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications - Volume 6: VISAPP, (VISIGRAPP 2017)},
year={2017},
pages={74-80},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006116200740080},
isbn={978-989-758-227-1},
}
in EndNote Style
TY - CONF
JO - Proceedings of the 12th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications - Volume 6: VISAPP, (VISIGRAPP 2017)
TI - Evaluation of the Degree of Malignancy of Lung Nodules in Computed Tomography Images
SN - 978-989-758-227-1
AU - Gonçalves L.
AU - Novo J.
AU - Cunha A.
AU - Campilho A.
PY - 2017
SP - 74
EP - 80
DO - 10.5220/0006116200740080