Intelligent Multi-sensor Arrays for Next Generation Diagnostic Biodevices

Hadar Ben-Yoav

2018

Abstract

Redox molecules play an essential role in many biological pathways, including energy metabolism, biosynthesis, and cell respiration. Moreover, a specific spectrum of redox molecules (comprising their type, concentration, and redox state) is involved in the development of diseases, including cancer. Thus, profiling the redox spectrum in the body is highly beneficial for a wide range of biomedical applications, from in vivo diagnostics to in situ monitoring of cell metabolism. Yet, the fundamental challenge lies within the ability to efficiently extract and analyze physiologically and medically relevant information from redox molecules in biofluids. This paper will discuss the advantageous approach to rapidly and continuously monitor redox molecules in biofluids using electrochemical lab-on-a-chip biodevices. The current approaches will be discussed to selectively measure redox molecules from biofluids without diminishing the rapid and continuous monitoring capabilities of these translational biodevices, i.e., by simultaneously analyzing multiple diagnostic redox biomarkers in a stand-alone operation, without any sample pretreatment or elimination of other interfering molecules. Then, the promising approach of using intelligent multi-sensor arrays will be highlighted for the rapid detection of a spectrum of redox molecules and the current challenges impeding their important utilization for next generation biomedical diagnostic devices.

Paper Citation

in Harvard Style

Ben-Yoav H. (2018). Intelligent Multi-sensor Arrays for Next Generation Diagnostic Biodevices. In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 1: BIODEVICES; ISBN 978-989-758-277-6, SciTePress, pages 236-240. DOI: 10.5220/0006653602360240

in Bibtex Style

@conference{biodevices18,
author={Hadar Ben-Yoav},
title={Intelligent Multi-sensor Arrays for Next Generation Diagnostic Biodevices},
booktitle={Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 1: BIODEVICES},
year={2018},
pages={236-240},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006653602360240},
isbn={978-989-758-277-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 1: BIODEVICES
TI - Intelligent Multi-sensor Arrays for Next Generation Diagnostic Biodevices
SN - 978-989-758-277-6
AU - Ben-Yoav H.
PY - 2018
SP - 236
EP - 240
DO - 10.5220/0006653602360240
PB - SciTePress