Design, Test and Fabrication of a Droplet based Microfluidic Device for Clinical Diagnostics

A. S. Moita, F. Jacinto, A. L. N. Moreira

2018

Abstract

Despite the intensive research performed towards the development of biomicrofuidic devices, information on the design, test and microfabrication of the devices is scarcely reported. Following our previous work, this paper describes the design, microfabrication and test of an electrowetting chip to transport and manipulate biosamples, towards the development of a microfluidic device for cancer diagnostics. As a first approach, experiments are performed to infer on the basic chip dimensions and configuration (size and positioning of the electrodes), allowing its best performance, evaluated based on droplet dynamics (spreading/receding diameter and contact line velocity). Then, to scale down this section, for its proper integration in the device, these basic dimensions are introduced as first guess values in a numerical model, used to optimize the distance between the electrodes, the thickness of the dielectric and the electric potential and frequency to be applied.

Paper Citation

in Bibtex Style

@conference{biodevices18,
author={A. S. Moita and F. Jacinto and A. L. N. Moreira},
title={Design, Test and Fabrication of a Droplet based Microfluidic Device for Clinical Diagnostics},
booktitle={Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 1: BIODEVICES},
year={2018},
pages={88-95},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006656600880095},
isbn={978-989-758-277-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 1: BIODEVICES
TI - Design, Test and Fabrication of a Droplet based Microfluidic Device for Clinical Diagnostics
SN - 978-989-758-277-6
AU - Moita A.
AU - Jacinto F.
AU - Moreira A.
PY - 2018
SP - 88
EP - 95
DO - 10.5220/0006656600880095
PB - SciTePress

in Harvard Style

Moita A., Jacinto F. and Moreira A. (2018). Design, Test and Fabrication of a Droplet based Microfluidic Device for Clinical Diagnostics. In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 1: BIODEVICES; ISBN 978-989-758-277-6, SciTePress, pages 88-95. DOI: 10.5220/0006656600880095