The Efficacy of Topical Application of Sumbawa Forest Honey for Wound Healing: Study on Incision Wound of Balb/C Male Mice

Nuria Wulandini, Dedianto Hidajat, Metta Octora

2018

Abstract

Topical application of honey has a well-known effect for wound healing. The benefits of honey include preventing infection, moisturizing, reducing inflammation, and stimulating tissue regulation and repair. One of the largest sources of honey in Indonesia is Sumbawa Island. In vitro studies suggest that Sumbawa forest honey possess antioxidant activity and ability to inhibit the growth of Staphylococcus aureus in surgical wound infections. The purpose of this study was to determine the efficacy of topical application of Sumbawa forest honey on incision wounds of BALB/c male mice. This was a double blind randomized control trial. The subjects of this study were BALB/c male mice that met eligibility criteria. The study group was divided into 3 groups; treatment group with topical application of Sumbawa forest honey, control group with 10% povidone iodine solution and group with no treatment. From the statistical analysis, p = 0.017 was obtained. There was a significant difference between the mean of wound length of this 3 groups. In the Mann-Whitney Post-hoc test results, there was a significant difference between the mean of wound length in the treatment group and the control group (p = 0.022) also between the treatment group and untreated group (p = 0.009). The topical application of Sumbawa forest honey can accelerate the healing of incision wound on BALB / c male mice.

Paper Citation

in Harvard Style

Wulandini N., Hidajat D. and Octora M. (2018). The Efficacy of Topical Application of Sumbawa Forest Honey for Wound Healing: Study on Incision Wound of Balb/C Male Mice.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 64-67. DOI: 10.5220/0008150900640067

in Bibtex Style

@conference{rcd18,
author={Nuria Wulandini and Dedianto Hidajat and Metta Octora},
title={The Efficacy of Topical Application of Sumbawa Forest Honey for Wound Healing: Study on Incision Wound of Balb/C Male Mice},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={64-67},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008150900640067},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - The Efficacy of Topical Application of Sumbawa Forest Honey for Wound Healing: Study on Incision Wound of Balb/C Male Mice
SN - 978-989-758-494-7
AU - Wulandini N.
AU - Hidajat D.
AU - Octora M.
PY - 2018
SP - 64
EP - 67
DO - 10.5220/0008150900640067