Differences of Minimum Erythema Dose (MED) in Fitzpatrick IV Skin Type Adults and Elderly with an Exposure of Narrowband Ultraviolet B (NB-UVB)

Arini Astasari Widodo, Tjut Nurul Alam Jacoeb, Aria Kekalih, Endi Novianto

2018

Abstract

The skin of the elderly is different compared to that of an adult due to aging, where such changes could influence the skin's response to ultraviolet exposure, including erythemal response. This difference could lead to MED change, which in turn affects the effectiveness of treatment modalities for skin diseases. This study aims to determine the difference between average MED in the elderly and adults with Fitzpatrick IV skin type, as well as the difference between 24 hours-MED and 48 hours-MED. MED calculations were based on skin erythemal responses relative to six different exposure doses of NB-UVB in elderly people aged over 60 years and adults aged 18-45 years. The irradiation is done with a Waldmann UV109 lamp with dosages starting from 300, 500, 700, 900, 1100, and 1300 mJ/cm 2 . Responses were examined at 24 hours and 48 hours post-irradiation by three different assessors. In the adult group, the mean of 24 hours-MED was 554 ± 182 mJ/cm 2 and 48 hours-MED was increased to 606 ± 167 mJ/cm 2 . In the elderly group, the mean of 24 hours-MED was 702 ± 340 mJ/cm 2 and 48 hours-MED was increased to 836 ± 341 mJ/cm 2 . The 24 hours-MED in the elderly group is higher compared to that of the adult group; however, the difference is not statistically significant (p=0.158). There is a statistically significant difference between 24 hours- MED and 48 hours-MED was found (<0.001) in the elderly group. The mean of 24 hours-MED in elderly and adults in this study could be applied clinically.

Paper Citation

in Harvard Style

Widodo A., Jacoeb T., Kekalih A. and Novianto E. (2018). Differences of Minimum Erythema Dose (MED) in Fitzpatrick IV Skin Type Adults and Elderly with an Exposure of Narrowband Ultraviolet B (NB-UVB).In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 73-77. DOI: 10.5220/0008151100730077

in Bibtex Style

@conference{rcd18,
author={Arini Astasari Widodo and Tjut Nurul Alam Jacoeb and Aria Kekalih and Endi Novianto},
title={Differences of Minimum Erythema Dose (MED) in Fitzpatrick IV Skin Type Adults and Elderly with an Exposure of Narrowband Ultraviolet B (NB-UVB)},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={73-77},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008151100730077},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Differences of Minimum Erythema Dose (MED) in Fitzpatrick IV Skin Type Adults and Elderly with an Exposure of Narrowband Ultraviolet B (NB-UVB)
SN - 978-989-758-494-7
AU - Widodo A.
AU - Jacoeb T.
AU - Kekalih A.
AU - Novianto E.
PY - 2018
SP - 73
EP - 77
DO - 10.5220/0008151100730077