Generalized Primary Anetoderma: A Rare Case

Dina Fatmasari, Reti Hindritiani, Kartika Ruchiatan, R. M. Rendi Ariezal E.

2018

Abstract

Anetoderma is a rare elastolytic disorder characterized by localized areas of slacks skins, that are reflection of a marked reduction or absence of dermal elastic fibers, that can appear as round or oval atrophic lesions, and wrinkling or sac-like protrutions. The predilection of lesions are on the trunk, thigh, and upper arms, and rarely occur on generalized distribution,. Primary anetoderma occur when there is no underlying cutaneous diseases, but could be associated with autoimmune diseases such as antiphospholipid syndrome and autoimmune connective tissue diseases. The aim of this report was to present a rare case of generalized primary anetoderma. A 19-year-old female had asymptomatic, multiple, small, circumscribed, round and oval atrophic lesions and sac-like protrution on almost all part of the body since 6 years ago without preceding cutaneous diseases. Histopathological examination with Verhoeff-Van Gieson elastin stain revealed fragmented and decreased of elastic fibers from superficial dermis until mid-dermis, and loss of elastic fibers in mid-dermis that confirmed the diagnosis of anetoderma. Laboratory test for autoimmune connective tissue diseases and antipospholipid syndrome were negative. Anetoderma is a benign disease, but can remain active for many years resulting in considerable aesthetic deformity, moreover in generalized distribution. Although no autoimmunologic abnormalities, long term follow-up is mandatory as an early warning signs of future symptoms of autoimmunity.

Paper Citation

in Harvard Style

Fatmasari D., Hindritiani R., Ruchiatan K. and Ariezal E. R. (2018). Generalized Primary Anetoderma: A Rare Case.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 446-450. DOI: 10.5220/0008159404460450

in Bibtex Style

@conference{rcd18,
author={Dina Fatmasari and Reti Hindritiani and Kartika Ruchiatan and R. M. Rendi Ariezal E.},
title={Generalized Primary Anetoderma: A Rare Case},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={446-450},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008159404460450},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Generalized Primary Anetoderma: A Rare Case
SN - 978-989-758-494-7
AU - Fatmasari D.
AU - Hindritiani R.
AU - Ruchiatan K.
AU - Ariezal E. R.
PY - 2018
SP - 446
EP - 450
DO - 10.5220/0008159404460450