Oral Hairy Leukoplakia: A Predictor and Prognostic Factor of HIV Infection

Yusuf Wibisono, Septiana Widyantari, Cita Rosita Sigit Prakoeswa

2018

Abstract

Introduction: Oral hairy leukoplakia (OHL), also known as benign hyperplasia of oral mucosa, is an asymptomatic white corrugated plaque that is most commonly found on the lateral borders of the tongue. This condition is caused by Epstein-Barr Virus (EBV). OHL is commonly found in immunocompromised patient, with the prevalence around 20-25% among HIV patients and indicates decline of CD4 counts. Case: A 29 year-old-male came to the Dermato-Venereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya with complaint of persistent asymptomatic whitish color on lateral side of his tongue. From history taking, the lesion was first appeared all over the tongue, and after consumption of antifungal treatment, the lesion subsided and persisted only on lateral border of the tongue. There were history of diarrhea, fever and cough for almost 1 month. He also has multiple sexual partners. From physical examination, we found painless white demarcated plaque with corrugated appearance on the left lateral border of the tongue. Further examination on HIV panels using three methods showed reactive result. Based on history taking, clinical and laboratory findings, the patient was diagnosed with OHL and HIV. The patient was treated with Acyclovir 800 mg, 5 times daily, and HAART (Duviral 2x1 tab + Neviral 1x1 tab). After 2 weeks of treatment, the lesion disappeared. Conclusion: The appearance of OHL is commonly associated with immunocompromised condition. The establishment of OHL has a diagnostic value for HIV infection. Systemic antiviral therapy and prevention of recurrence using antiretroviral medication showed satisfying result.

Paper Citation

in Harvard Style

Wibisono Y., Widyantari S. and Prakoeswa C. (2018). Oral Hairy Leukoplakia: A Predictor and Prognostic Factor of HIV Infection.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 505-509. DOI: 10.5220/0008160805050509

in Bibtex Style

@conference{rcd18,
author={Yusuf Wibisono and Septiana Widyantari and Cita Rosita Sigit Prakoeswa},
title={Oral Hairy Leukoplakia: A Predictor and Prognostic Factor of HIV Infection},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={505-509},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008160805050509},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Oral Hairy Leukoplakia: A Predictor and Prognostic Factor of HIV Infection
SN - 978-989-758-494-7
AU - Wibisono Y.
AU - Widyantari S.
AU - Prakoeswa C.
PY - 2018
SP - 505
EP - 509
DO - 10.5220/0008160805050509