The Level of Zinc Serum after Oral Zinc on Mice with Escherichia Coli LPS- Induced Diarrhea

Sulaiman Yusuf, Yati Soenarto, Muhammad Juffrie, Mudatsir, Wiryatun Lestariana

2018

Abstract

The level of zinc requirements will increase due to infection, for formation of immune function and new cells. The advantage of Zinc is maintain the integrity of the intestinal mucosa through its function in cell regeneration and membrane stability. The aim of this study is to determine the level of zinc serum after oral zinc on mice diarrheal induce E.Coli-LPS. This study used a controlled trial experimental design in the laboratory. Sample of 20 mice were randomly divided into 4 groups:1). Control group was given standard foods, 2). Trial group was given E.Coli-LPS 2.5 mg/kg/oral once on day-1, 3). Preventive group was given E.Coli-LPS once 2.5 mg/kg/oral once on day-1 + 30 mg/kg/oral of zinc once daily for 12 days. 4). Therapy group was given E.Coli-LPS 2.5 mg/kg/oral once on day-1, if diarrheal was given 30 mg/kg/oral of zinc once daily for 12 days. Blood samples of mice were taken through the orbital sinus on the 0, 5th, 10thhour, 4th, 8th and 12thday. Data are presented in tables and graphic. We found that higher levels of zinc in the preventive and therapy group especially on 4th, 8th and 12th day. I conclusion, oral administration of zinc increase serum zinc levels, especially in control and experimental groups.

Paper Citation

in Harvard Style

Yusuf S., Soenarto Y., Juffrie M., Lestariana W. and Mudatsir. (2018). The Level of Zinc Serum after Oral Zinc on Mice with Escherichia Coli LPS- Induced Diarrhea.In Proceedings of the 2nd Syiah Kuala International Conference on Medicine and Health Sciences - Volume 1: SKIC-MHS, ISBN 978-989-758-438-1, pages 163-167. DOI: 10.5220/0008788201630167

in Bibtex Style

@conference{skic-mhs18,
author={Sulaiman Yusuf and Yati Soenarto and Muhammad Juffrie and Wiryatun Lestariana and Mudatsir},
title={The Level of Zinc Serum after Oral Zinc on Mice with Escherichia Coli LPS- Induced Diarrhea},
booktitle={Proceedings of the 2nd Syiah Kuala International Conference on Medicine and Health Sciences - Volume 1: SKIC-MHS,},
year={2018},
pages={163-167},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008788201630167},
isbn={978-989-758-438-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Syiah Kuala International Conference on Medicine and Health Sciences - Volume 1: SKIC-MHS,
TI - The Level of Zinc Serum after Oral Zinc on Mice with Escherichia Coli LPS- Induced Diarrhea
SN - 978-989-758-438-1
AU - Yusuf S.
AU - Soenarto Y.
AU - Juffrie M.
AU - Lestariana W.
AU - Mudatsir.
PY - 2018
SP - 163
EP - 167
DO - 10.5220/0008788201630167